This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation.
Cell reports · 2023
Latest funding
- $140,000
Determining the Impact of Dual-Agonist Incretin Therapies on Diastolic Function in a Rodent Model of Diabetic Cardiomyopathy.
CIHR · 2025 · Supervisor
- $120,000
Linking fuel utilization to diastolic dysfunction: The role of SERCA acetylation in diabetic cardiomyopathy
CIHR · 2025 · Supervisor
- $810,900
Immunometabolism as a Mediator of Differential Outcomes Regarding Saturated Versus Unsaturated Fat-Based Ketogenic Diets in Obesity
CIHR · 2025 · Nominated PI
1 publications.
Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation.
Mocholi E, Russo L, Gopal K, Ramstead AG, Hochrein SM, Vos HR, Geeven G, Adegoke AO, Hoekstra A, van Es RM, Pittol JR, Vastert S, Rutter J, Radstake T, van Loosdregt J, Berkers C, Mokry M, Anderson CC, O'Connell RM, Vaeth M, Ussher J, Burgering BMT, Coffer PJ
Determining the Impact of Dual-Agonist Incretin Therapies on Diastolic Function in a Rodent Model of Diabetic Cardiomyopathy.
Principal investigators: Scheidl, Taylor B
Keywords: Anti-Diabetic Pharmaceuticals; Diabetes; Diabetic Cardiomyopathy; Echocardiography; Transgenic Mouse Models
Linking fuel utilization to diastolic dysfunction: The role of SERCA acetylation in diabetic cardiomyopathy
Principal investigators: King, Alexa N
Keywords: Acetylation; Co-Immunoprecipitation; Diabetes; Diabetic Cardiomyopathy; Diastolic Dysfunction; Echocardiography; Fat Oxidation; Glucose Oxidation; Metabolism; Mitochondria
Immunometabolism as a Mediator of Differential Outcomes Regarding Saturated Versus Unsaturated Fat-Based Ketogenic Diets in Obesity
Principal investigators: Ussher, John R; Richard, Caroline
Keywords: Diabetes; Inflammation; Ketogenic Diets; Metabolism; Obesity; Saturated Fats; Unsaturated Fats
Canada Research Chair - Tier 2
Principal investigators: Ussher, John R
Keywords: Crc
Aging & Metabolic Flexibility
Principal investigators: Ussher, John R
Keywords: Aging; Metabolic Flexibility; Mitochondria; Muscle Function; Pyruvate Dehydrogenase
Elucidating the Caridovascular Biology of Growth Differentiation Factor 15 in Type 2 Diabetes
Principal investigators: Chan, Jordan S
Keywords: Cardiovascular; Type 2 Diabetes
Elucidating the mechanism underlying the cardioprotective actions of growth differentiation factor 15 in diabetic cardiomyopathy
Principal investigators: Chan, Jordan S
Keywords: Cardiac Function; Diabetes; Diabetic Heart Disease; Growth Differentiation Factor 15; Inflammation; Obesity
Discovery and Development of Brain-Sparing Inhibitors of Succinyl-CoA:3-Ketoacid CoA Transferase
Principal investigators: Ussher, John R
Keywords: Chemical Synthesis; Ketone Body Oxidation; Molecular Modeling; Preclinical Drug Development; Structure-Guided Drug Design; Succinyl Coa:3-Ketoacid Coa Transferase
A Stress Activated Znf281 Signalling Pathway Can be Therapeutically Targeted to Prevent Chemotherapy-Induced Cardiotoxicity
Principal investigators: Sutendra, Gopinath
Keywords: Apoptosis; Cardiac Function; Cardio-Oncology; Drug Discovery; Heart Failure; P53; Redox
Development of Succinyl-CoA:3-ketoacid CoA Transferase (SCOT) Inhibitors for the Treatment of Type 2 Diabetes
Principal investigators: Tabatabaei Dakhili, Seyed Amirhossein
Keywords: Ketone Bodies; Metabolism; Obesity; Type 2 Diabetes
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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