Maria Ioannou

Cryopreservation of In Vitro Models of the Blood-Brain Barrier

Principal investigators: Elliott, Janet A

Keywords: Astrocytes; Blood-Brain Barrier; Brain Microvascular Endothelial Cells (Bmec); Brain Vascular Pericytes; Cells Cultured In 2d Layers; Cerebral Microvascular Endothelial Cells; Cryobiology; Cryopreservation; In Vitro Drug Testing; Induced Pluripotent Stem Cell (Ipsc)-Derived Bmec

Exploring how lipid alterations promote Parkinson's disease pathology through ectosomes

Principal investigators: Ioannou, Maria S

Keywords: Extracellular Vesicles; Lipid Alterations; Live-Cell Imaging; Parkinson'S Disease; Quantitative Microscopy; Synuclein Transmission

Canada Research Chair - Tier 2

Principal investigators: Ioannou, Maria S

Keywords: Crc

Investigating the mechanisms and function of lipid release from neurons during oxidative stress

Principal investigators: Ralhan, Isha

Keywords: Fatty Acid Toxicity; Ferroptosis; Fluorescence Microscopy; Glial Cell Health; Lipo-Apoptosis; Lysosomal Exocytosis; Neurodegeneration; Neuronal Fatty Acid Release; Oxidative Stress; Primary Cultures

The regulation and function of lipid metabolism in astrocytes

Principal investigators: Ioannou, Maria

Keywords: astrocyte; fatty acid; trafficking; microscopy; mitochondria; atp; vesicle; exocytosis; lipid droplet; nmda

Investigating the neuroprotective mechanisms of lipid transfer from neurons to glia during oxidative stress

Principal investigators: Ioannou, Maria S

Keywords: Apolipoproteins; Exocytosis; Fatty Acid; Ferroptosis; Glia; Lipid Peroxidation; Lipotoxicity; Neuron; Oxidative Stress; Secretion

The regulation and function of lipid metabolism in astrocytes

Principal investigators: Ioannou, Maria

The mechanisms and function of neuronal lipid particle release during ischemic stroke

Principal investigators: Ioannou, Maria S

Keywords: Apolipoprotein; Exocytosis; Ferroptosis; Lipotoxicity; Stroke