Stefan Pukatzki, University of Alberta

Research

Antibiotics Bacterial Genetics Bacterial Pathogenesis Microbial Competition T6ss Type Vi Secretion System Vibrio Cholerae Antibiotic Resistance

Latest papers

Vibrio cholerae endemic to the lower Rio Grande Delta segregate into urban and rural phylotypes.
Scientific reports · 2025 · senior author
Commensal pathogen competition impacts host viability.
Proceedings of the National Academy of Sciences of the United States of America · 2018 · senior author
Adaptor Proteins of Type VI Secretion System Effectors.
Trends in microbiology · 2017 · senior author

All 21 publications

Latest funding

Microbial Competition in Disease: Mechanisms and Applications
CIHR · 2014 · Nominated PI
$2,129,231
Host-Mediated Control of Virulence and Immunity Genes in Vibrio cholerae
CIHR · 2014 · Nominated PI
$654,884
The Vibrio cholerae Type VI Protein Secretion System and its Role in Microbial Competition
CIHR · 2010 · Nominated PI
$777,148

All 3 grants and awards

21 publications.

01

Vibrio cholerae endemic to the lower Rio Grande Delta segregate into urban and rural phylotypes.

Provenzano D, Turner JW, Duran-Gonzalez J, Laughlin DA, Kitaoka M, Unterweger D, Silva D, Trevino V, Gonzales MF, Ermolinsky B, Pukatzki S

Scientific reports2025Senior author

DOI: 10.1038/s41598-025-04734-6 PMID: 40603335

02

Commensal pathogen competition impacts host viability.

Fast D, Kostiuk B, Foley E, Pukatzki S

Proceedings of the National Academy of Sciences of the United States of America2018Senior author

DOI: 10.1073/pnas.1802165115 PMID: 29915049

03

Adaptor Proteins of Type VI Secretion System Effectors.

Unterweger D, Kostiuk B, Pukatzki S

Trends in microbiology2017Senior author

DOI: 10.1016/j.tim.2016.10.003 PMID: 27856117

04

Bile Salts Modulate the Mucin-Activated Type VI Secretion System of Pandemic Vibrio cholerae.

Bachmann V, Kostiuk B, Unterweger D, Diaz-Satizabal L, Ogg S, Pukatzki S

PLoS neglected tropical diseases2015Senior author

DOI: 10.1371/journal.pntd.0004031 PMID: 26317760

05

Chimeric adaptor proteins translocate diverse type VI secretion system effectors in Vibrio cholerae.

Unterweger D, Kostiuk B, Ötjengerdes R, Wilton A, Diaz-Satizabal L, Pukatzki S

The EMBO journal2015Senior author

DOI: 10.15252/embj.201591163 PMID: 26194724

06

A multidrug resistance plasmid contains the molecular switch for type VI secretion in Acinetobacter baumannii.

Weber BS, Ly PM, Irwin JN, Pukatzki S, Feldman MF

Proceedings of the National Academy of Sciences of the United States of America2015

DOI: 10.1073/pnas.1502966112 PMID: 26170289

07

The Cpx system regulates virulence gene expression in Vibrio cholerae.

Acosta N, Pukatzki S, Raivio TL

Infection and immunity2015

DOI: 10.1128/iai.03056-14 PMID: 25824837

08

The Vibrio cholerae Cpx envelope stress response senses and mediates adaptation to low iron.

Acosta N, Pukatzki S, Raivio TL

Journal of bacteriology2015

DOI: 10.1128/jb.01957-14 PMID: 25368298

09

The Vibrio cholerae type VI secretion system employs diverse effector modules for intraspecific competition.

Unterweger D, Miyata ST, Bachmann V, Brooks TM, Mullins T, Kostiuk B, Provenzano D, Pukatzki S

Nature communications2014Senior author

DOI: 10.1038/ncomms4549 PMID: 24686479

10

Vibrio cholerae as a predator: lessons from evolutionary principles.

Pukatzki S, Provenzano D

Frontiers in microbiology2013First author

DOI: 10.3389/fmicb.2013.00384 PMID: 24368907

Microbial Competition in Disease: Mechanisms and Applications

Nominated PICIHR2014Foundation Grant

Principal investigators: Pukatzki, Stefan

Keywords: Antibiotic Resistance; Antibiotics; Bacterial Genetics; Bacterial Pathogenesis; Cholera; Microbial Competition; Microbiome; T6ss; Type Vi Secretion System; Vibrio Cholerae

$2,129,231

Host-Mediated Control of Virulence and Immunity Genes in Vibrio cholerae

Nominated PICIHR2014Operating Grant

Principal investigators: Pukatzki, Stefan

Keywords: Antibiotics; Bacterial Genetics; Bacterial Pathogenesis; Microbial Competition; T6ss; Type Vi Secretion System; Vibrio Cholerae

$654,884

The Vibrio cholerae Type VI Protein Secretion System and its Role in Microbial Competition

Nominated PICIHR2010Operating Grant

Principal investigators: Pukatzki, Stefan

Keywords: Bacterial Protein Secretion; Bacterial Toxins; Biological Membranes; Dictyostelium Discoideum; Gene Regulation; Host-Pathogen Interactions; Microbial Pathogenesis; Persistence; Vibrio Cholerae; Virulence Factors

$777,148

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Edan Foley

Medical Microbiology and Immunology

1 shared papers, latest 2018

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Subject: Prospective PhD student: Antibiotics Dear Professor Pukatzki, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Vibrio cholerae endemic to the lower Rio Grande Delta segregate into urban and rural phylotypes." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]