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Research
Latest papers
Ketogenic diet for infantile epileptic spasms.
Epilepsia open · 2025 · senior author
Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy.
PLoS biology · 2025
Protocol for continuous video-EEG/EMG recording to study brain function in neonatal rats.
STAR protocols · 2024
Latest funding
- $1,128,376
The role of the acid sensing ion channel (ASIC) 1a in the mechanism of action of the ketogenic diet in infantile spasms
CIHR · 2021 · Principal investigator
- $1,119,995
Ketone-Mediated Epigenetic Modulation of Mitochondrial Function in Epileptic Brain
CIHR · 2016 · Co-investigator
7 publications.
Ketogenic diet for infantile epileptic spasms.
Scantlebury MH, Choudhary A, Ng AC, Gavrilovici C
Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy.
Dogra D, Phan VA, Zhang S, Gavrilovici C, DiMarzo N, Narang A, Ibhazehiebo K, Kurrasch DM
Protocol for continuous video-EEG/EMG recording to study brain function in neonatal rats.
Choudhary A, Gavrilovici C, Ng AC, Scantlebury MH
Mechanisms of infantile epileptic spasms syndrome: What have we learned from animal models?
Ng AC, Choudhary A, Barrett KT, Gavrilovici C, Scantlebury MH
kcna1a mutant zebrafish model episodic ataxia type 1 (EA1) with epilepsy and show response to first-line therapy carbamazepine.
Dogra D, Meza-Santoscoy PL, Gavrilovici C, Rehak R, de la Hoz CLR, Ibhazehiebo K, Rho JM, Kurrasch DM
A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target.
Ibhazehiebo K, Gavrilovici C, de la Hoz CL, Ma SC, Rehak R, Kaushik G, Meza Santoscoy PL, Scott L, Nath N, Kim DY, Rho JM, Kurrasch DM
Ndel1 and Reelin Maintain Postnatal CA1 Hippocampus Integrity.
Jiang Y, Gavrilovici C, Chansard M, Liu RH, Kiroski I, Parsons K, Park SK, Teskey GC, Rho JM, Nguyen MD
The role of the acid sensing ion channel (ASIC) 1a in the mechanism of action of the ketogenic diet in infantile spasms
Principal investigators: Scantlebury, Morris; Gavrilovici, Cezar; Pittman, Quentin J
Keywords: Acid Sensing Ion Channels; Animal Models; Crispr; Eeg; Epilepsy; Fluorescent Microscopy; Gaba Inhibition; Ketogenic Diet; Neurophysiology
Ketone-Mediated Epigenetic Modulation of Mitochondrial Function in Epileptic Brain
Principal investigators: Rho, Jong M; Kim, DoYoung; Teskey, G. Cam C
Keywords: Cyclophilin D; Epilepsy; Epileptogenesis; Histone Deacetylase; Ketogenic Diet; Ketone Bodies; Mitochondria; Mitochondrial Permeability Transition; Sirtuin 3; Therapeutics
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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