Jennifer Corcoran

Coronavirus nucleocapsid proteoforms inhibit antiviral biomolecular condensates

Principal investigators: Corcoran, Jennifer A

Keywords: Alternate Proteoforms; Antiviral Rna Granules; Dsrna-Induced Foci; Genetic Economy; Human Coronaviruses; Processing Bodies; Sars-Cov-2; Stress Granules; Virus-Host Interactions

Unraveling the role of extracellular matrix dysregulation in age-related fibrotic and inflammatory pulmonary disease

Principal investigators: Kai, FuiBoon

Keywords: Actomyosin Network; Age-Related Diseases; Biophysical Properties Of Cells; Extracellular Matrix; Idiopathic Pulmonary Fibrosis; Inflammation; Mechanosignaling; Tissue Stiffness

The Kaposi's sarcoma-associated herpesvirus (KSHV) kaposin locus promotes latency establishment after primary infection

Principal investigators: Corcoran, Jennifer A

Keywords: Bi-Functional Rna; Dna Damage Response; Genome Replication; Herpesviruses; Kaposi'S Sarcoma-Associated Herpesvirus; Kaposin Locus; Primary Infection; Recombinant Viruses; Tumourigenesis; Virus-Host Interactions

Oxygen-Regulated Tissue Culturing for Accurate In Virto Cell Analyses

Principal investigators: Riabowol, Karl

A mechanoresponsive signalling pathway disassembles processing bodies

Principal investigators: Corcoran, Jennifer

Intravital imaging of COVID-19 lungs to visualize pathogenic differences between SARS-CoV-2 variants of concern

Principal investigators: Kubes, Paul; Corcoran, Jennifer A; McDonald, Braedon A

Keywords: Brain; Endothelium; Heart; Imaging; Innate Immunity; Lungs; Neutrophils; Platelets; Sars-Cov2; Variants Of Concern

SARS-CoV-2 infection disassembles processing bodies to manipulate antiviral responses

Principal investigators: Mulloy, Rory P

Keywords: Antiviral Response; Ribonucleoprotein Granules; Virology

Imaging COVID-19 Lungs to Uncover Therapies

Principal investigators: Kubes, Paul; Corcoran, Jennifer A; Gillrie, Mark R; Jenne, Craig N; Kelly, Margaret M; McDonald, Braedon A; Mody, Christopher H; Peters, Nathan

Keywords: Endothelium; Innate Immunity; Intravital Imaging; Lungs; Monocytes; Neutrophils; Nk Cells; Organoids; Patelets; Vasculature

The kaposin gene cluster drives KSHV latent and lytic infection cycles and viral tumourigenesis

Principal investigators: Kleer, Mariel

Keywords: Molecular Biology; Viral-Tumourigenesis; Virology