Faculty profile
Dustin King
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Research
Latest papers
Development of Tunable Mechanism-Based Carbasugar Ligands that Stabilize Glycoside Hydrolases through the Formation of Transient Covalent Intermediates.
ACS catalysis · 2024
Latest funding
- $960,076
The role of MYORG in primary brain calcification.
CIHR · 2026 · Co-investigator
- $979,200
Molecular regulation of O-GlcNAc Transferase (OGT)
CIHR · 2024 · Co-investigator
- $994,500
CO2-dependent protein carboxylation as a biochemical mechanism of CO2 sensing in pathogens
CIHR · 2024 · Nominated PI
1 publications.
Development of Tunable Mechanism-Based Carbasugar Ligands that Stabilize Glycoside Hydrolases through the Formation of Transient Covalent Intermediates.
Bhosale S, Kandalkar S, Gilormini PA, Akintola O, Rowland R, Adabala PJP, King D, Deen MC, Chen X, Davies GJ, Vocadlo DJ, Bennet AJ
The role of MYORG in primary brain calcification.
Principal investigators: Vocadlo, David
Keywords: Brain Calcification; Enzymes; Glycobiology; Glycomics; Glycoside Hydrolase; Hipsc; Mass Spectrometry; Pharmacological Chaperone; Primary Familial Brain Calcification; Proteomics
Molecular regulation of O-GlcNAc Transferase (OGT)
Principal investigators: Vocadlo, David
Keywords: Allosteric Regulation; Binding Assays; Carbohydrates; Cell-Based Assays; Enzyme Assays; Enzyme Inhibitors; Enzyme Regulation; Glycobiology; Peptide Binding Site; X-Ray Structural Biology
CO2-dependent protein carboxylation as a biochemical mechanism of CO2 sensing in pathogens
Principal investigators: King, Dustin T
Keywords: Biochemistry; Chemical Biology; Chemoproteomics; Co2; Co2 Sensing; Mass Spectrometry; Microbial Metabolite Sensing; Pathogens; Post-Translational Modifications; Transcriptomics
Advancement of a Genetically Encoded CO2 Sensor for Monitoring the Cyanobacterial Carbon Concentrating Mechanism
Principal investigators: King, Dustin DT
Keywords: bacterial carbon capture; carbon concentrating mechanism; co2 sensing; cyanobacteria; fluorescent protein; genetically encoded protein sensor; genetic engineering; genetic screen; structure-based protein engineering; x-ray crystallography
Exploring lysine-cysteine crosslinks as redox sensitive biochemical switches in proteins
Principal investigators: King, Dustin
Keywords: lysine-cysteine bridges; mass spectrometry; O2; post-translational modification; protein oxidation; protein thermostability; proteomics; redox network; redox sensor; structural biology
Exploring lysine-cysteine crosslinks as redox sensitive biochemical switches in proteins
Principal investigators: King, Dustin
Identification of CO2 sensors in cyanobacteria – toward improved carbon capture.
Principal investigators: King, Dustin
Keywords: protein carboxylation; metabolite sensing; protein sensor; chemoproteomics; post-translational modification; cyanobacteria; carbon fixation; protein biochemistry; carbon dioxide; genomics
Identification of CO2 sensors in cyanobacteria - toward improved carbon capture.
Principal investigators: King, Dustin
Keywords: protein carboxylation metabolite sensing protein sensor chemoproteomics post-translational modification cyanobacteria carbon fixation protein biochemistry carbon dioxide genomics
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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