Harald Hutter, Simon Fraser University

Research

Axon Guidance C. Elegans Cadherins Collagens Genetics Nervous System Development

Latest papers

Laminin is uniformly expressed in basement membranes surrounding longitudinal axon tracts in the ventral and dorsal nerve cords in C. elegans.
microPublication biology · 2025 · first author
GExplore 1.5: a comprehensive Caenorhabditis elegans database for the analysis of gene function with a new user-friendly web interface.
Database : the journal of biological databases and curation · 2025 · first author
wrk-1 and rig-5 control pioneer and follower axon navigation in the ventral nerve cord of Caenorhabditis elegans in a nid-1 mutant background.
Genetics · 2023 · senior author

All 25 publications

Latest funding

The molecular basis of pioneer and follower axon navigation in Caenorhabditis elegans
NSERC · 2023 · Principal investigator
$80,000
High-pressure freezing unit for visualizing cellular ultrastructure by electron microscopy
NSERC · 2019 · Co-investigator
$150,000
The molecular basis of neuronal circuit formation
NSERC · 2017 · Principal investigator
$240,000

All 11 grants and awards

25 publications.

01

Laminin is uniformly expressed in basement membranes surrounding longitudinal axon tracts in the ventral and dorsal nerve cords in C. elegans.

Hutter H

microPublication biology2025First author

DOI: 10.17912/micropub.biology.001766 PMID: 40880990

02

GExplore 1.5: a comprehensive Caenorhabditis elegans database for the analysis of gene function with a new user-friendly web interface.

Hutter H, Moosavi M, Mafi N

Database : the journal of biological databases and curation2025First author

DOI: 10.1093/database/baaf044 PMID: 40996714

03

wrk-1 and rig-5 control pioneer and follower axon navigation in the ventral nerve cord of Caenorhabditis elegans in a nid-1 mutant background.

Feresten AH, Bhat JM, Yu AJ, Zapf R, Rankin CH, Hutter H

Genetics2023Senior author

DOI: 10.1093/genetics/iyac187 PMID: 36573271

04

lron-11 guides axons in the ventral nerve cord of Caenorhabditis elegans.

Kokan N, Witt S, Sandhu S, Hutter H

PloS one2022Senior author

DOI: 10.1371/journal.pone.0278258 PMID: 36449480

05

Mutations in the Spliceosome Component prp-6 and Overexpression of cdh-5 Suppress Axon Guidance Defects of cdh-4 Mutants in Caenorhabditis elegans.

Aburegeba Z, Pan J, Hutter H

Neuroscience insights2022Senior author

DOI: 10.1177/26331055221123346 PMID: 36090596

06

ccd-5, a novel cdk-5 binding partner, regulates pioneer axon guidance in the ventral nerve cord of Caenorhabditis elegans.

Feresten AH, Bhat JM, Yu AJ, Zapf R, Safi H, Au V, Flibotte S, Doell C, Moerman DG, Hawkins N, Rankin CH, Hutter H

Genetics2022Senior author

DOI: 10.1093/genetics/iyac024 PMID: 35143653

07

Multiple Pathways Act Together To Establish Asymmetry of the Ventral Nerve Cord in Caenorhabditis elegans.

Taylor J, Hutter H

Genetics2019Senior author

DOI: 10.1534/genetics.119.301999 PMID: 30792268

08

CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans.

Au V, Li-Leger E, Raymant G, Flibotte S, Chen G, Martin K, Fernando L, Doell C, Rosell FI, Wang S, Edgley ML, Rougvie AE, Hutter H, Moerman DG

G3 (Bethesda, Md.)2019

DOI: 10.1534/g3.118.200778 PMID: 30420468

09

Formation of longitudinal axon pathways in Caenorhabditis elegans.

Hutter H

Seminars in cell & developmental biology2019First author

DOI: 10.1016/j.semcdb.2017.11.015 PMID: 29141179

10

The transmembrane collagen COL-99 guides longitudinally extending axons in C. elegans.

Taylor J, Unsoeld T, Hutter H

Molecular and cellular neurosciences2018Senior author

DOI: 10.1016/j.mcn.2018.03.003 PMID: 29550247

The molecular basis of pioneer and follower axon navigation in Caenorhabditis elegans

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Hutter, Harald

Keywords: axon guidance; cadherin; C. elegans; development; genetics; IgCAM; neuron; receptor

$80,000

High-pressure freezing unit for visualizing cellular ultrastructure by electron microscopy

Co-investigatorNSERC2019Research Tools and Instruments

Principal investigators: Beh, Christopher

$150,000

The molecular basis of neuronal circuit formation

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Hutter, Harald

$240,000

A super-resolution microscope for visualizing cellular structure and dynamics

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Beh, Christopher

$150,000

Functional analysis of the novel axon guidance genes fmi-1, cdh-4 and col-99

Nominated PICIHR2013Operating Grant

Principal investigators: Hutter, Harald

Keywords: Axon Guidance; C. Elegans; Cadherins; Collagens; Genetics; Nervous System Development

$658,205

Next-generation sequencer for evolutionary genomics

Co-investigatorNSERC2012Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Hart, Michael

$136,083

Systematic identification of receptors required for nervous system development in C. elegans

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Hutter, Harald

$140,000

Symposium in Honor of Dr. Don Riddle's Retirement

Co-investigatorCIHR2010Meetings, Planning and Dissemination Grant: Genetics

Principal investigators: Taubert, Stefan

Keywords: Aging; C. Elegans; Dauer Formation; Genetics; Model Organisms

$5,000

The molecular basis for directed outgrowth of pioneer and follower axons in C. elegans

Nominated PICIHR2008Operating Grant

Principal investigators: Hutter, Harald

Keywords: Defects In Human Brain Development; Formation Of Neuronal Circuits; Genetics; Neuronal Development

$664,970

Ultra-sensitive camera for live cell imaging under low-light conditions

Principal investigatorNSERC2007Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Hutter, Harald

$43,975

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Donald Moerman

Zoology

1 shared papers, latest 2015

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2023

Subject: Prospective PhD student: Axon Guidance Dear Professor Hutter, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Laminin is uniformly expressed in basement membranes surrounding longitudinal axon tracts in the ventral and dorsal nerve cords in C. elegans." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "The molecular basis of pioneer and follower axon navigation in Caenorhabditis elegans" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]