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Research
Latest papers
A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.
Proceedings of the National Academy of Sciences of the United States of America · 2005
Latest funding
- $841,500
Correcting early vascular dysfunction to improve cardiovascular outcomes in type 1 diabetes
CIHR · 2020 · Co-investigator
- $753,525
Determining the role of histone modifications in mediating transcriptional consistency in beta-cells and in diabetes pathogenesis
CIHR · 2016 · Nominated PI
- $198,000
TrxG complexes in pancreas endocrine-cell specification
NSERC · 2016 · Principal investigator
1 publications.
A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.
Siddiqui AS, Khattra J, Delaney AD, Zhao Y, Astell C, Asano J, Babakaiff R, Barber S, Beland J, Bohacec S, Brown-John M, Chand S, Charest D, Charters AM, Cullum R, Dhalla N, Featherstone R, Gerhard DS, Hoffman B, Holt RA, Hou J, Kuo BY, Lee LL, Lee S, Leung D, Ma K, Matsuo C, Mayo M, McDonald H, Prabhu AL, Pandoh P, Riggins GJ, de Algara TR, Rupert JL, Smailus D, Stott J, Tsai M, Varhol R, Vrljicak P, Wong D, Wu MK, Xie YY, Yang G, Zhang I, Hirst M, Jones SJ, Helgason CD, Simpson EM, Hoodless PA, Marra MA
Correcting early vascular dysfunction to improve cardiovascular outcomes in type 1 diabetes
Principal investigators: Devlin, Angela M; Bernatchez, Pascal N; Panagiotopoulos, Constadina
Keywords: Aortic Stiffness; Blood Pressure; Children; Endothelial Cells; Type 1 Diabetes
Determining the role of histone modifications in mediating transcriptional consistency in beta-cells and in diabetes pathogenesis
Principal investigators: Hoffman, Brad G
Keywords: Beta-Cell; Chromatin Structure; Diabetes; Histone Modifications; Transcriptional Regulation; Trithorax Complex
TrxG complexes in pancreas endocrine-cell specification
Principal investigators: Hoffman, Brad
Determining Myt3's role in beta-cell maturation, function and inflammatory response.
Principal investigators: Hoffman, Brad G
Keywords: Apoptosis; Diabetes; Gene Regulation; Glucose-Stimulated Insulin Secretion; Transcription Factors
Functional analysis of Myt3's role in Beta-cell transcriptional networks and diabetes
Principal investigators: Hoffman, Brad G
Keywords: Apoptosis; Diabetes; Gene Regulation; Proliferation; Transcription Factors
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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