Faculty profile

Dan Luciani

ResearcherCellular and Physiological SciencesUniversity of British Columbia

This profile is built from public research funding records (CIHR, NSERC and SSHRC). We have not imported them from a University of British Columbia directory, so their publications, courses and email address may be missing. Find their university profile.

Signals and details

Research

Apoptosis Diabetes Islet Biology Beta Cells Biological Sex Endoplasmic Reticulum Stress Extracellular Vesicles Genetics

Latest funding

Leveraging biological sex and genetics for beta cell-directed precision medicine in type 1 diabetes
CIHR · 2022 · Principal investigator
$1,750,000
The interplay of apoptosis proteins, mitochondria and premature senescence in beta-cell fate and diabetes
CIHR · 2021 · Nominated PI
$837,675
Beta-cell resilience to insulin-driven stress in type 1 diabetes: Lessons from both sexes
CIHR · 2020 · Principal investigator
$10,000

All 6 grants and awards

Leveraging biological sex and genetics for beta cell-directed precision medicine in type 1 diabetes

Principal investigatorCIHR2022Team Grant: CIHR-JDRF Type 1 Diabetes and Precision Medicine

Principal investigators: Rideout, Elizabeth J; Johnson, James D; Luciani, Dan S; Thompson, Peter; Verchere, Bruce C

Keywords: Beta Cells; Biological Sex; Endoplasmic Reticulum Stress; Extracellular Vesicles; Genetics; Insulin; Mrna Translation; Precision Medicine; Protein Processing; Type 1 Diabetes

$1,750,000

The interplay of apoptosis proteins, mitochondria and premature senescence in beta-cell fate and diabetes

Nominated PICIHR2021Project Grant

Principal investigators: Luciani, Dan S

Keywords: Apoptosis; Autophagy / Mitophagy; Bcl-2 Family Proteins; Beta-Cell Biology; Cellular Stress; Diabetes; High Content Imaging; Islet Biology; Mitochondrial Morphology And Function; Senescence

$837,675

Beta-cell resilience to insulin-driven stress in type 1 diabetes: Lessons from both sexes

Principal investigatorCIHR2020Team Grant: DM/TS - CIHR-JDRF - ß-cell and Pancreatic Islet Physiology - LOI

Principal investigators: Johnson, James D; Luciani, Dan S; Rideout, Elizabeth J; Thompson, Peter; Verchere, Bruce C

Keywords: Autophagy And Lysosomal Protein Homeostasis; Extracellular Vesicles And Exosomes; Human Islet Studies; Insulin Transcription; Insulin Translation; Molecular Mechanisms Of Type 1 Diabetes; Pancreatic Beta-Cell Biology; Pre-Clinical Genetically Engineered Mouse Models; Prohormone Processing

$10,000

Metabolic regulation of immune defenses in newborns

Co-investigatorCIHR2019Project Grant

Principal investigators: Lavoie, Pascal

Keywords: Energy Metabolism; Innate Immunity; Monocytes; Ontogeny; Premature Infant; Translation

$1,013,816

Control of beta-cell mitochondrial physiology and adaptation by core anti-apoptosis proteins

Nominated PICIHR2015Operating Grant

Principal investigators: Luciani, Dan S

Keywords: Apoptosis; Autophagy; Diabetes; High Fat Diet; In Vivo Glucose Homeostasis; Islet Biology; Knockout Mouse Models; Live Cell Microscopy; Metabolic Stress; Mitochondrial Physiology

$631,125

Control of beta-cell mitochondrial physiology by core anti-apoptosis proteins

Nominated PICIHR2011Operating Grant

Principal investigators: Luciani, Dan S

Keywords: Apoptosis; Diabetes; In Vivo Glucose Homeostasis; Islet Biology; Knockout Mouse Models; Live Cell Microscopy; Metabolic Stress; Mitochondrial Physiology

$351,470

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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