Research
Read how they describe their research on their University of Toronto profile.
Latest funding
GLP-1 Receptor Agonists as a Preventive Strategy for Clonal Hematopoiesis-Driven Hematologic Cancers
CIHR · 2025 · Principal investigator
- $140,000
Mechanistic Study of Central Glucagon-like peptide-1 Receptor Signaling in Modulating Systemic Inflammation
CIHR · 2025 · Supervisor
- $1,999,985
Prevention of Adiposity-related Cancers via Biology and Evidence Triangulation (PROBE)
CIHR · 2025 · Principal investigator
No publications available.
GLP-1 Receptor Agonists as a Preventive Strategy for Clonal Hematopoiesis-Driven Hematologic Cancers
Principal investigators: Chan, Steven M; Drucker, Daniel J; Xie, Stephanie Z
Keywords: Cancer Prevention; Clonal Fitness; Clonal Hematopoiesis; Diabetes; Glp1 Receptor Agonist; Hematological Malignancies; Hematopoietic Stem Cells; Inflammation; Metabolism; Myeloid Neoplasms
Mechanistic Study of Central Glucagon-like peptide-1 Receptor Signaling in Modulating Systemic Inflammation
Principal investigators: Ren, Wenran
Keywords: Central Glp-1 Receptor Signaling; Diabetes And Obesity; Glp-1 Receptor Agonist; Neuro-Immune Regulation; Systemic Inflammation
Prevention of Adiposity-related Cancers via Biology and Evidence Triangulation (PROBE)
Principal investigators: Hung, Rayjean; Patton, Ian T; Sockalingam, Sanjeev; Drucker, Daniel J; Retnakaran, Ravi R
Keywords: Biological Mechanisms; Cancer Prevention; Circulating Biomarker; Glp-1; Metabolic Health; Obesity; Risk Prediction
GLP-1 Receptor Agonists: Exploring Adverse Drug Events in Older Adults
Principal investigators: Rochon, Paula A; Stall, Nathan M
Keywords: Adverse Drug Events; Aging; Glp-1 Receptor Agonists; Older Women; Ozempic; Rybelsus
The anti-inflammatory actions of glucagon-like peptide 1-based medicines in the brain
Principal investigators: Fang, Susanna
Keywords: Astrocytes; Central Nervous System; Glucagon-Like Peptide 1; Glucagon-Like Peptide 1-Based Medicines; Lipopolysaccharide; Neuroinflammation; Neurological Disorders; Neurons; Proteomics; Single-Cell Rna Sequencing
Role of the vascular smooth muscle GLP-1 receptor in renoprotection
Principal investigators: Medak, Kyle D
Keywords: Diabetes; Glp-1; Hypertension; Kidney; Mice
Direct and indirect mechanisms of GLP-1 action
Principal investigators: Drucker, Daniel J
Keywords: Atherosclerosis; Diabetes; Gut Hormones; Metabolic Liver Disease; Obesity
Elucidating the role of the central nervous system as a metabolic target for new metabolism-regulating drugs acting through the glucose-dependent insulinotropic polypeptide receptor (GIPR)
Principal investigators: Hammoud, Rola
Keywords: Appetite-Control; Central Nervous System; Gipr Agonist And Antagonist Treatments; Glucagon-Like Peptide 1 Receptor (Glp-1r) Agonist; Glucose Tolerance; Glucose-Dependent Insulinotropic Polypeptide Receptor (Gipr); Neuron-Specific Gipr Knockout Mice; Obesity; Peripheral Nervous System; Targeted Drug Therapy
Using novel transplantation strategies and HLA-edited hypoimmunogenic hPSCs to develop a superior islet-like product for T1D treatment
Principal investigators: Nostro, Maria Cristina; Drucker, Daniel J; Korbutt, Gregory S; Pepper, Andrew R; Vasconcelos, Sara N
Keywords: Beta Cells; Directed Differentiation; Hla-Editing; Human Pluripotent Stem Cells; Humanized Mice; Regenerative Medicine; Transplantation; Type 1 Diabetes
Immunometabolic roles and therapeutic potential of glucose-dependent insulinotropic polypeptide(GIP)
Principal investigators: Drucker, Daniel J; Varol, Chen
Keywords: Atherosclerosis; Diabetes; Heart Disease; Inflammation; Obesity
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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Profile data last refreshed on September 26, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.