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Research
Latest papers
Global StationaryOT: trajectory inference for aging time courses of single-cell snapshots.
Bioinformatics (Oxford, England) · 2026 · senior author
Trajectory inference for a branching SDE model of cell differentiation via lineage tracing.
Journal of mathematical biology · 2026 · senior author
Spatial Transcriptomics Brings New Challenges and Opportunities for Trajectory Inference.
Annual review of biomedical data science · 2025 · senior author
Latest funding
- $849,150
Illuminating the genetic forces driving development by profiling with single cell transcriptomics at thousands of time-points
CIHR · 2021 · Nominated PI
- $30,000
Illuminating the genetic forces driving development by profiling with single cell transcriptomics at thousands of time-points
CIHR · 2021 · Nominated PI
- $205,000
Towards a mathematical theory of development
NSERC · 2020 · Principal investigator
18 publications.
Global StationaryOT: trajectory inference for aging time courses of single-cell snapshots.
Boyle C, Ventre E, Schiebinger G
Trajectory inference for a branching SDE model of cell differentiation via lineage tracing.
Ventre E, Forrow A, Gadhiwala N, Chakraborty P, Angel O, Schiebinger G
Spatial Transcriptomics Brings New Challenges and Opportunities for Trajectory Inference.
Heitz M, Ma Y, Kubal S, Schiebinger G
The dynamics of hematopoiesis over the human lifespan.
Li H, Côté P, Kuoch M, Ezike J, Frenis K, Afanassiev A, Greenstreet L, Tanaka-Yano M, Tarantino G, Zhang S, Whangbo J, Butty VL, Moiso E, Falchetti M, Lu K, Connelly GG, Morris V, Wang D, Chen AF, Bianchi G, Daley GQ, Garg S, Liu D, Chou ST, Regev A, Lummertz da Rocha E, Schiebinger G, Rowe RG
Single-Cell Transcriptomics Reveals Evolutionary Reconfiguration of Embryonic Cell Fate Specification in the Sea Urchin Heliocidaris erythrogramma.
Massri AJ, Berrio A, Afanassiev A, Greenstreet L, Pipho K, Byrne M, Schiebinger G, McClay DR, Wray GA
Tracking the gene expression programs and clonal relationships that underlie mast, myeloid, and T lineage specification from stem cells.
Michaels YS, Major MC, Bonham-Carter B, Zhang J, Heydari T, Edgar JM, Siu MM, Greenstreet L, Vilarrasa-Blasi R, Kim S, Castle EL, Forrow A, Ibanez-Rios MI, Zimmerman C, Chung Y, Stach T, Werschler N, Knapp DJHF, Vento-Tormo R, Schiebinger G, Zandstra PW
Reprogramming of cells during embryonic transfating: overcoming a reprogramming block.
Berrio A, Miranda E, Massri AJ, Afanassiev A, Schiebinger G, Wray GA, McClay DR
Neuropeptide signalling orchestrates T cell differentiation.
Hou Y, Sun L, LaFleur MW, Huang L, Lambden C, Thakore PI, Geiger-Schuller K, Kimura K, Yan L, Zang Y, Tang R, Shi J, Barilla R, Deng L, Subramanian A, Wallrapp A, Choi HS, Kye YC, Ashenberg O, Schiebinger G, Doench JG, Chiu IM, Regev A, Sharpe AH, Kuchroo VK
Reconstruction of single-cell lineage trajectories and identification of diversity in fates during the epithelial-to-mesenchymal transition.
Cheng YC, Zhang Y, Tripathi S, Harshavardhan BV, Jolly MK, Schiebinger G, Levine H, McDonald TO, Michor F
Cellular proliferation biases clonal lineage tracing and trajectory inference.
Bonham-Carter B, Schiebinger G
Illuminating the genetic forces driving development by profiling with single cell transcriptomics at thousands of time-points
Principal investigators: Schiebinger, Geoffrey
Keywords: C. Elegans; Developmental Process; Dna Barcodes; Embryo Barcodes; Embryonic Development; Gene Expression; High Density Time-Course; Lineage Tracing; Single Cell Rna-Seq; Trajectory Inference
Illuminating the genetic forces driving development by profiling with single cell transcriptomics at thousands of time-points
Principal investigators: Schiebinger, Geoffrey
Keywords: C. Elegans; Developmental Process; Dna Barcodes; Embryo Barcodes; Embryonic Development; Gene Expression; High Density Time-Course; Lineage Tracing; Single Cell Rna-Seq; Trajectory Inference
Towards a mathematical theory of development
Principal investigators: Schiebinger, Geoffrey
Cytokine networks controlling myeloid cell mediated immunosuppression in colon cancer.
Principal investigators: Harder, Kenneth W
Keywords: Cancer; Colorectal Cancer; Cytokines; Dendritic Cells; Developmental Trajectories; Immunosuppression; Immunotherapy; Mdscs; Phagocytes; Systems Biology
Towards a mathematical theory of development
Principal investigators: Schiebinger, Geoffrey
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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