Faculty profile
Ghassan Hamarneh
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Research
Latest papers
Adversarial Erasing Enhanced Multiple Instance Learning (siMILe): Discriminative Identification of Oligomeric Protein Structures in Single Molecule Localization Microscopy.
Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2026 · senior author
Diffusing caveolin-1 scaffolds regulate mechanosignalling.
Nature cell biology · 2026
DataCurator.jl: efficient, portable and reproducible validation, curation and transformation of large heterogeneous datasets using human-readable recipes compiled into machine-verifiable templates.
Bioinformatics advances · 2023 · senior author
Latest funding
- $952,426
Role of MERCs and Mitophagy in Cancer Progression
CIHR · 2022 · Co-investigator
- $50,000
COVID-19 Variant Supplement - Computer-aided discovery of synergistic drug combinations with Remdevisir for COVID-19 through mechanism-based drug repurposing and combinatorial organoid screening.
CIHR · 2021 · Co-investigator
- $90,000
COVID-19 Variant Network - Computer-aided discovery of synergistic drug combinations with Remdevisir for COVID-19 through mechanism-based drug repurposing and combinatorial organoid screening.
CIHR · 2021 · Co-investigator
11 publications.
Adversarial Erasing Enhanced Multiple Instance Learning (siMILe): Discriminative Identification of Oligomeric Protein Structures in Single Molecule Localization Microscopy.
Hallgrimson C, Li YL, Shou CA, Cardoen B, Lim J, Wong TH, Khater IM, Nabi IR, Hamarneh G
Diffusing caveolin-1 scaffolds regulate mechanosignalling.
Mani SK, Tardif N, Rossier O, Khater IM, Zhou X, Breton V, Nunes Vicente F, Radhakrishnan AV, Gracia C, Gonzalez Troncoso P, Brito I, Ruez R, Dewulf M, Hamarneh G, Nabi IR, Cuniasse P, Sens P, Giannone G, Blouin CM, Lamaze C
DataCurator.jl: efficient, portable and reproducible validation, curation and transformation of large heterogeneous datasets using human-readable recipes compiled into machine-verifiable templates.
Cardoen B, Ben Yedder H, Lee S, Nabi IR, Hamarneh G
SPECHT: Self-tuning Plausibility based object detection Enables quantification of Conflict in Heterogeneous multi-scale microscopy.
Cardoen B, Wong T, Alan P, Lee S, Matsubara JA, Nabi IR, Hamarneh G
3D fascicle orientations in triceps surae.
Rana M, Hamarneh G, Wakeling JM
Modeling brain activation in fMRI using group MRF.
Ng B, Hamarneh G, Abugharbieh R
Perception-based visualization of manifold-valued medical images using distance-preserving dimensionality reduction.
Hamarneh G, McIntosh C, Drew MS
MRI-based 3D shape analysis of thigh muscles patients with chronic obstructive pulmonary disease versus healthy adults.
HajGhanbari B, Hamarneh G, Changizi N, Ward AD, Reid WD
n-SIFT: n-dimensional scale invariant feature transform.
Cheung W, Hamarneh G
Efficient interactive 3D Livewire segmentation of complex objects with arbitrary topology.
Poon M, Hamarneh G, Abugharbieh R
Role of MERCs and Mitophagy in Cancer Progression
Principal investigators: Nabi, Ivan R
Keywords: Autophagy; Cancer Progression; Endoplasmic Reticulum; Gp78; Machine Learning; Membrane Contact Sites; Mitochondria; Reactive Oxygen Species; Super-Resolution Microscopy
COVID-19 Variant Supplement - Computer-aided discovery of synergistic drug combinations with Remdevisir for COVID-19 through mechanism-based drug repurposing and combinatorial organoid screening.
Principal investigators: Cherkasov, Artem; Jean, François
Keywords: Drug And Natural Product Repurposing; Enable High-Quality Data On Existing Covid-19 Treatment; Enhance Canadian Engagement In Large Scale Trials; Enhance Engagement With Middle-Income & Low-Income Countries; Evidences For Clinical & Public Health Decision Makers; Idenitfy Remdesivir Synergistic Drugs; National And International Coordination For Sharing Of Data; New Covid-19 Treatment For Interventions And Prevention; Rapid Deployment Of Existing Research Platforms; Sex As A Biological Variable
COVID-19 Variant Network - Computer-aided discovery of synergistic drug combinations with Remdevisir for COVID-19 through mechanism-based drug repurposing and combinatorial organoid screening.
Principal investigators: Cherkasov, Artem; Jean, François
Keywords: Drug And Natural Product Repurposing; Enable High-Quality Data On Existing Covid-19 Treatment; Enhance Canadian Engagement In Large Scale Trials; Enhance Engagement With Middle-Income & Low-Income Countries; Evidences For Clinical & Public Health Decision Makers; Idenitfy Remdesivir Synergistic Drugs; National And International Coordination For Sharing Of Data; New Covid-19 Treatment For Interventions And Prevention; Rapid Deployment Of Existing Research Platforms; Sex As A Biological Variable
Using super-resolution microscopy to define the role of caveolin-1 in cancer
Principal investigators: Nabi, Ivan R; Hamarneh, Ghassan
Keywords: Caveolae; Caveolin-1; Focal Adhesion; Machine Learning; Pkm2; Super-Resolution Microscopy; Tumor Cell Metabolism; Tumor Cell Migration
Computer-aided discovery of synergistic drug combinations with Remdevisir for COVID-19 through mechanism-based drug repurposing and combinatorial organoid screening.
Principal investigators: Cherkasov, Artem; Jean, François
Keywords: Drug And Natural Product Repurposing; Enable High-Quality Data On Existing Covid-19 Treatment; Enhance Canadian Engagement In Large Scale Trials; Enhance Engagement With Middle-Income & Low-Income Countries; Evidences For Clinical & Public Health Decision Makers; Idenitfy Remdesivir Synergistic Drugs; National And International Coordination For Sharing Of Data; New Covid-19 Treatment For Interventions And Prevention; Rapid Deployment Of Existing Research Platforms; Sex As A Biological Variable
Super-resolution microscopy network analysis: Drug target validation for cystic fibrosis
Principal investigators: Nabi, Ivan R; Arbuckle, John; Hamarneh, Ghassan; Hanrahan, John W; Wiseman, Paul W
Keywords: Cftr; Cystic Fibrosis; Drug Validation; Machine Learning; Network Analysis; Storm; Super-Resolution Microscopy
Caveolin-1 regulation of focal adhesion tension and the breast cancer cell response to matrix stiffness
Principal investigators: Nabi, Ivan R
Keywords: Breast Cancer; Caveolin-1; Extracellular Matrix Stiffness; Focal Adhesions; Membrane Domains; Metastasis; Single Molecule Localization Microscope; Super Resolution Microscopy; Tumor Cell Migration; Vinculin Tension
Caveolin-1 regulation of focal adhesion tension and the breast cancer cell response to matrix stiffness
Principal investigators: Nabi, Ivan R
Keywords: Caveolin-1; Extracellular Matrix Stiffness; Focal Adhesions; Mechanical Stress; Membrane Domains; Metastasis; Single Molecule Localization Microscope; Super Resolution Microscopy; Tumor Cell Migration; Vinculin
Development of a confocal endoscope for gastrointestinal cancer diagnosis
Principal investigators: Chiao, Mu; Chou, Keng-Chang; Hamarneh, Ghassan; Nagamune, Ryozo; Tai, Isabella T; Zeng, Haishan
Keywords: Confocal Imaging; Gastrointestinal Tract Endoscope; Mems; Optical Scanners
Integrating Quantitative Imaging Methods and Genomic Biomarkers to Assess the Therapeutic Response of Cancers
Principal investigators: Benard, Francois
Keywords: Quantitative Imaging
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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