Faculty profile
Janel Kopp
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
DNA methylation-based classification uncovers acinar and ductal origins for KPC-derived PDAC cell lines.
Cancer letters · 2026
Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors.
Cell stem cell · 2023
Transformation of SOX9+ cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma.
Scientific reports · 2021
Latest funding
- $67,500
Diet induced obesity and the risk of ductal cell transformation
CIHR · 2025 · Nominated PI
- $898,876
Hyperinsulinemia in pancreatic cancer progression and mortality
CIHR · 2025 · Nominated PI
- $120,000
The role of insulin in pancreatic cancer progression and tumor metabolism
CIHR · 2025 · Supervisor
3 publications.
DNA methylation-based classification uncovers acinar and ductal origins for KPC-derived PDAC cell lines.
Zoi I, Rajput M, Holguín-Horcajo A, Haidar M, Brusa D, Chu K, Xie J, Shields M, Ferreira S, Stanger B, Attardi LD, Kopp J, Stemmler MP, Nicolle R, Rovira M, Jacquemin P
Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors.
Magenheim J, Maestro MA, Sharon N, Herrera PL, Murtaugh LC, Kopp J, Sander M, Gu G, Melton DA, Ferrer J, Dor Y
Transformation of SOX9+ cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma.
Chen J, Debebe A, Zeng N, Kopp J, He L, Sander M, Stiles BL
Diet induced obesity and the risk of ductal cell transformation
Principal investigators: Kopp, Janel
Keywords: Cancer
Hyperinsulinemia in pancreatic cancer progression and mortality
Principal investigators: Kopp, Janel
Keywords: Diabetes; Glucose; Hyperinsulinemia; Insulin; Kras Inhibitors; Kras/Mapk/Erk; Orthotopic Tumor Transplantation; Pancreatic Ductal Adenocarcinoma; Patient Derived Tumor Organoids; Pi3k/Akt/Mtor
The role of insulin in pancreatic cancer progression and tumor metabolism
Principal investigators: Lin, Jeffrey
Keywords: Cancer Treatment; Insulin And Hyperinsulinemia; Metabolomics; Mouse Model Of Pancreatic Cancer; Pancreatic Cancer; Proteomics; Systemic Metabolic Disorders; Tumor Metabolism
Role of inflammation during the genesis of intraductal papillary mucinous neoplasia associated pancreatic ductal adenocarcinoma
Principal investigators: Kopp, Janel
Keywords: Cancer Initiation; Cancer Progression; Cystic Precancerous Lesions; Cytotoxic T Cells In Cancer; Immune Suppressive Cell Types In Cancer; Intraductal Papillary Mucinous Neoplasia (Ipmn); Kras; Mouse Models Of Cancer Development; Pancreatic Cancer; Pten
Testing the causality of hyperinsulinemia in pancreatic cancer
Principal investigators: Zhang, Anni
Keywords: Insulin; Insulin Receptors; Insulin Resistance; Kras; Lifestyle; Mouse Models; Obesity; Pancreatic Cancer; Type 2 Diabetes
Molecular mechanisms regulating developmental maturation of pancreatic ductal cells
Principal investigators: Kopp, Janel
Using genetically engineered mouse models to define variables producing pancreatic ductal adenocarcinoma heterogeneity
Principal investigators: Kopp, Janel
Keywords: Biomarkers; Diagnostic Gene Signatures; Mouse Genetic Models; Pancreatic Cancer; Pancreatic Ductal Adenocarcinoma; Premalignant Lesions; Tumor Heterogeneity; Tumorigenesis
Molecular And Cellular Mechanisms Leading To Pancreatic Cancer Heterogeneity
Principal investigators: Kopp, Janel
Keywords: Acinar Cell; Cellular Differentiation; Developmental Genetics; Ductal Cell; Genetically Engineered Mouse Models; Intraductal Papillary Mucinous Neoplasia; Mouse Genetics; Pancreatic Cancer; Precancerous Lesions; Tumor Heterogeneity
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.