Faculty profile
Kenneth Harder
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Research
Latest funding
- $120,000
Development of Potent Cancer Vaccines Using a Multi-Omic, Spatially Resolved, Barcoded Lipid Nanoparticle Screening Platform
CIHR · 2025 · Supervisor
- $100,000
Optimization of next-generation RNA vaccines for pandemic preparedness
CIHR · 2022 · Co-investigator
- $822,375
Cytokine networks controlling myeloid cell mediated immunosuppression in colon cancer.
CIHR · 2020 · Nominated PI
Development of Potent Cancer Vaccines Using a Multi-Omic, Spatially Resolved, Barcoded Lipid Nanoparticle Screening Platform
Principal investigators: Yu, Cayden
Keywords: Cancer Immunotherapy; Cancer Vaccines; Immune Profiling; Lipid Nanoparticles; Multi-Omics; Single-Cell Rna Sequencing; Spatial Transcriptomics
Optimization of next-generation RNA vaccines for pandemic preparedness
Principal investigators: Blakney, Anna
Keywords: Humoral Immunity; Lipid Nanoparticles; Messenger Rna; Nanomedicine; Pandemic Preparedness; Polyethylene Glycol; Reactogenicity; Rna; Self-Amplifying Rna; Vaccines
Cytokine networks controlling myeloid cell mediated immunosuppression in colon cancer.
Principal investigators: Harder, Kenneth W
Keywords: Cancer; Colorectal Cancer; Cytokines; Dendritic Cells; Developmental Trajectories; Immunosuppression; Immunotherapy; Mdscs; Phagocytes; Systems Biology
Tyrosine kinase control of phagocytes in acute and chronic inflammation
Principal investigators: Harder, Kenneth W
Keywords: Adcc/Adcp; Breast Cancer; Checkpoint Blockade; Immunotherapy; Inhibitory Signalling; Lung Cancer; Mass Cytometry; Monocytes; Phagocytes; Tyrosine Kinase
Regulation of receptor mobility and spatial organization: Key factors in B cell activation
Principal investigators: Gold, Michael R; Chou, Keng-Chang; Coombs, Daniel
Keywords: B Cell Receptor; B Lymphocytes; Membrane Proteins; Nanoclusters/Protein Islands; Receptor Mobility; Signal Transduction; Single Particle Tracking; Super-Resolution Microscopy; Toll-Like Receptors
Lipid nanomedicines for health and disease
Principal investigators: Cullis, Pieter R
Keywords: Anticancer; Drug Delivery System; Gene Therapy; Immunosuppressant; Lipid Nanoparticles; Mrna; Nanomedicine; Sirna; Small Molecule Drugs; Trigger Release
Phagocyte control of innate lymphocytes and adaptive immune responses
Principal investigators: Harder, Kenneth W
Keywords: Dendritic Cells/Phagocytes; Epigenetics; Innate Lymphocytes; Microbiome; Mouse Models Of Disease; Mucosal Immune Responses; Natural Killer Cells; Pattern Recognition Receptors; Phagocyte Control Of Ilcs; Tyrosine Kinase
CANADA RESEARCH CHAIRHOLDER/TITULAIRE DES CHAIRES DE RECERCHE DU CANADA
Principal investigators: Harder, Kenneth W
Keywords: Crc
Control of autoimmunity by altered inhibitory signalling in antigen presenting cells.
Principal investigators: Roberts, Morgan
Keywords: Antigen Presenting Cells; Autoantibodies; Autoimmunity; Dendritic Cells; Glomerulonephropathy; Immunogenetics; Lyn Tyrosine Kinase; Systemic Lupus Erythematosus
Role of Lyn in the mononuclear phagocyte regulation of intestinal inflammation
Principal investigators: Tirling, Chelsea O
Keywords: Animal Work; Autoimmunity; Cell Culture; Immunology; Inflammatory Bowel Disease; Lamina Propria; Phagocytes
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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