Pere Santamaria, University of British Columbia

Research

Immunometabolism Immunomodulation Insulin Islet Macrophages Metabolomics Sex Differences T Cells

Latest papers

TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes.
Journal of immunology (Baltimore, Md. : 1950) · 2010
The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation.
Journal of theoretical biology · 2009
Modeling competition among autoreactive CD8+ T cells in autoimmune diabetes: implications for antigen-specific therapy.
International immunology · 2006

All 3 publications

Latest funding

Immunometabolism in diabetes: harnessing metabolic crosstalk between islets and immune cells for therapy
CIHR · 2021 · Principal investigator
$2,000,000
Immunometabolism in diabetes: harnessing metabolic crosstalk between islets and immune cells for therapy
CIHR · 2020 · Principal investigator
$10,000

All 2 grants and awards

3 publications.

01

TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes.

Zhang Y, Lee AS, Shameli A, Geng X, Finegood D, Santamaria P, Dutz JP

Journal of immunology (Baltimore, Md. : 1950)2010

DOI: 10.4049/jimmunol.0901814 PMID: 20393135

02

The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation.

Khadra A, Santamaria P, Edelstein-Keshet L

Journal of theoretical biology2009

DOI: 10.1016/j.jtbi.2008.09.019 PMID: 18950644

03

Modeling competition among autoreactive CD8+ T cells in autoimmune diabetes: implications for antigen-specific therapy.

Marée AF, Santamaria P, Edelstein-Keshet L

International immunology2006

DOI: 10.1093/intimm/dxl040 PMID: 16728432

Immunometabolism in diabetes: harnessing metabolic crosstalk between islets and immune cells for therapy

Principal investigatorCIHR2021Team Grant: Diabetes Mechanisms and Translational Solutions - General Pool

Principal investigators: Verchere, Bruce C; Hosak, Ramya; Klein Geltink, Ramon; Levings, Megan K; Santamaria, Pere; Tsai, Sue Y

Keywords: Immunometabolism; Immunomodulation; Insulin; Islet; Macrophages; Metabolomics; Sex Differences; T Cells; T Regulatory Cells; Type 1 Diabetes

$2,000,000

Immunometabolism in diabetes: harnessing metabolic crosstalk between islets and immune cells for therapy

Principal investigatorCIHR2020Team Grant: DM/TS - CIHR-JDRF - ß-cell and Pancreatic Islet Physiology - LOI

Principal investigators: Verchere, Bruce C; Klein Geltink, Ramon; Levings, Megan K; Santamaria, Pere; Tsai, Sue Y

Keywords: Immunometabolism; Immunomodulation; Insulin; Islet; Macrophages; Metabolomics; Sex Differences; T Cells; T Regulatory Cells; Type 1 Diabetes

$10,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2021

Subject: Prospective PhD student: Immunometabolism Dear Professor Santamaria, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes." (2010), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Immunometabolism in diabetes: harnessing metabolic crosstalk between islets and immune cells for therapy" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]