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Latest papers
Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model.
Cerebral cortex (New York, N.Y. : 1991) · 2024
Behavioral Classification of Sequential Neural Activity Using Time Varying Recurrent Neural Networks.
bioRxiv : the preprint server for biology · 2023
Dendritic spines and pre-synaptic boutons are stable despite local deep hypothermic challenge and re-warming in vivo.
PloS one · 2012 · senior author
Latest funding
- $120,000
Multi-Scale Investigation of Cellular, Circuit, and Behavioral Phenotypes in Huntington's Disease (HD)
CIHR · 2025 · Supervisor
- $1,013,625
Investigating altered sensorimotor processing in Huntington disease
CIHR · 2023 · Co-investigator
- $100,000
Investigating altered sensorimotor processing in Huntington disease
CIHR · 2022 · Co-investigator
3 publications.
Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model.
Bottom-Tanzer S, Corella S, Meyer J, Sommer M, Bolaños L, Murphy T, Quiñones S, Heiney S, Shtrahman M, Whalen M, Oren R, Higley MJ, Cardin JA, Noubary F, Armbruster M, Dulla C
Behavioral Classification of Sequential Neural Activity Using Time Varying Recurrent Neural Networks.
Zhang Y, Mitelut C, Arpin DJ, Vaillancourt D, Murphy T, Saxena S
Dendritic spines and pre-synaptic boutons are stable despite local deep hypothermic challenge and re-warming in vivo.
Xie Y, Chen S, Murphy T
Multi-Scale Investigation of Cellular, Circuit, and Behavioral Phenotypes in Huntington's Disease (HD)
Principal investigators: Kwok, Oi Ting (Christy)
Keywords: 2-Photon Imaging; Behavioural Neuroscience; Excitation-Inhibition Balance; Huntington'S Disease; In Vivo Calcium Imaging; Motor Dysfunction; Mouse Models; Neural Circuits; Novel Paradigms; Sensory Processing
Investigating altered sensorimotor processing in Huntington disease
Principal investigators: Raymond, Lynn A
Keywords: Cortex; Gabaergic Inhibition; Genetic Mouse Models; Huntington Disease; Mesoscale Imaging; Multi-Electrode Recording; Nmda Receptor; Optogenetics; Sensory Processing; Synaptic Transmission
Investigating altered sensorimotor processing in Huntington disease
Principal investigators: Raymond, Lynn A
Keywords: Circuits; Cortex; Gabaergic Inhibition; Genetic Mouse Models; Huntington Disease; Mesoscale Imaging; Multielectrode Recording; Nmda Receptor; Sensory Processing; Synaptic Transmission
Tools for assessing shared sensory experience in interacting mice.
Principal investigators: Murphy, Timothy
3-dimensional representation of mouse movement and rapid interaction with cortical brain activity to describe and shape behavior to improve outcome from stroke: insights from real and synthetic data approaches.
Principal investigators: Murphy, Timothy H
Keywords: Behavior; Connectivity; Cortex; Imaging; Markerless Tracking; Mouse; Optogenetics; Stroke
Neuron-Glia interactions in brain disease
Principal investigators: MacVicar, Brian A
Keywords: Astrocyte; Cerebral Blood Flow; Cytotoxic Edema; Hippocampus; Intracellular Calcium; Intracellular Chloride; Microglia; Neurovascular Coupling; Pannexin; Two Photon Imaging
Enabling novel circuit-based treatments for stroke: insights from cortical circuit monitoring and manipulation in mouse models.
Principal investigators: Murphy, Timothy H
Keywords: 2-Photon; Cortical Circuit; Imaging; Motor System; Mouse; Optogenetics; Plasticity; Sensorimotor; Sensory System; Stroke
Aberrant NMDA receptor and synaptic signaling in vulnerability to neurodegeneration: Focus on Huntington disease
Principal investigators: Raymond, Lynn A
Keywords: Acute Brain Slice; Electrophysiology; Huntington Disease; Neurodegeneration; Nmda Receptor; Optogenetics; Primary Neuronal Culture; Striatum; Synaptic Plasticity; Western Blot
Canadian Stroke Network (2006 Renewal Competition)
Principal investigators: Hakim, Antoine
Using optogenetics to identify and regulate cortical circuits that lead to interhemispheric inhibition after stroke
Principal investigators: Silasi, Gergely
Keywords: Behaviour; Chronic Window; Interhemispheric Inhibition; Motor Cortex; Motor Mapping; Optogenetics; Plasticity; Recovery; Stroke; Transcranial Magnetic Stimulation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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