Craig Brown

Endothelial calcium signalling as a regulator of capillary stalling: Investigating mechanisms of microvascular of blood flow control and therapeutic strategies for ischemic stroke

Principal investigators: Hancock, Dominique A

Keywords: Capillary Stalling / No-Reflow Phenomenon; Cerebral Microcirculation; Endothelial Calcium Signalling; In Vivo Calcium Imaging; Ischemic Stroke; Neurovascular Health And Recovery; Therapeutic Strategies In Stroke; Two-Photon Microscopy; Vascular Biology

Understanding the role of endothelial calcium waves in regulating microcirculatory function in brain health and injury due to stroke

Principal investigators: Brown, Craig E

Keywords: Calcium; Capillaries; Cerebral Blood Flow; Chemogenetics (Dreadds); Endothelial Cells; Ischemic Stroke; Mouse; Pericytes; Recanalization/Reflow; Two-Photon Microscopy

High density silicon probes for electrophysiological recording of activity in hundreds of neurons across brain regions

Principal investigators: Brown, Craig

Keywords: Aging; Cerebrovascular; Computational Neuroscience; Cortex; Dopamine; Electrophysiology; Evolution; Movement; Neurobiology; Neuroscience

Preserving microcirculation and function in the diabetic brain

Principal investigators: Brown, Craig E

Keywords: Capillary; Cerebral Blood Flow; Cognition; Diabetes; Inflammation; Interleukin-10; Mice; Neutrophil; Stroke; Two-Photon Microsocpy

Understanding the impact of capillary obstructions on brain angio-architecture and function

Principal investigators: Brown, Craig

An optogenetic approach for rewiring thalamocortical circuits to restore function after stroke

Principal investigators: Brown, Craig E

Keywords: 2-Photon Microscopy; Calcium Imaging; Imaging; Mice; Neural Plasticity; Optogenetics; Somatosensory Cortex; Stroke Recovery; Thalamus

Postnatal development of nicotinic acetylcholine receptor signaling in the cerebral cortex

Principal investigators: Brown, Craig

Promoting thalamocortical plasticity to improve recovery of function after cortical ischemia

Principal investigators: Tennant, Kelly

Keywords: Axonal Plasticity; In Vivo Imaging; Ischemia; Recovery Of Function; Sensorimotor Behaviour; Stroke; Thalamocortical Projections; Thalamus; Two-Photon Imaging; Vascular Plasticity

Impact of diabetes on brain function and recovery from ischemic stroke

Principal investigators: Brown, Craig E

Keywords: 2-Photon Microscopy; Angiogenesis; Behaviour; Blood Flow; Diabetes; Imaging; Neural Plasticity; Recovery Of Function; Somatosensory Cortex; Stroke

Implantable telemetric devices for electrophysiological and behavioural research using rodent disease models

Principal investigators: Delaney, Kerry