Faculty profile

Bradley Doble

ResearcherPediatrics and Child HealthUniversity of Manitoba

This profile is built from public research funding records (CIHR, NSERC and SSHRC). We have not imported them from a University of Manitoba directory, so their publications, courses and email address may be missing. Find their university profile.

Signals and details

Research

Cell adhesion Cell fate determination Cell signalling Cellular differentiation Genome editing Intercellular communication Micropatterning Organoids

Latest funding

Impact of exposure to hyperglycemia during pregnancy on offspring airway smooth muscle contractility and the activity of RhoA
CIHR · 2023 · Co-investigator
$784,125
Impact of maternal hyperglycemia on offspring airway smooth muscle contractility and the activity of RhoA.
CIHR · 2022 · Co-investigator
$100,000
Building a broken heart: 3D bioprinted, stem cell derived cardiac muscle to study and treat rare metabolic diseases
SSHRC · 2022 · Co-investigator
$125,000

All 7 grants and awards

Impact of exposure to hyperglycemia during pregnancy on offspring airway smooth muscle contractility and the activity of RhoA

Co-investigatorCIHR2023Project Grant

Principal investigators: Pascoe, Christopher D

Keywords: Airway Smooth Muscle; Animal Model; Asthma; Developmental Origins; Gestational Diabetes; Rhoa; Stem Cell

$784,125

Impact of maternal hyperglycemia on offspring airway smooth muscle contractility and the activity of RhoA.

Co-investigatorCIHR2022Project Grant

Principal investigators: Pascoe, Christopher D

Keywords: Airway Smooth Muscle; Animal Model; Asthma; Developmental Origins; Gestational Diabetes; Rhoa; Stem Cell

$100,000

Building a broken heart: 3D bioprinted, stem cell derived cardiac muscle to study and treat rare metabolic diseases

Co-investigatorSSHRC2022New Frontiers in Research Fund - Exploration

Principal investigators: West, Adrian

Keywords: 3d bioprinting; tissue engineering; rare disease; cardiac muscle; cardiac disease; genetic disease

$125,000

Determine how the interaction between SARS-CoV-2 spike protein and angiotensin-converting enzyme 2 (ACE2) affect viral spread and the severity of COVID-19 outcomes.

Co-investigatorCIHR2021Operating Grant: Emerging COVID-19 Research Gaps and Priorities - Variants

Principal investigators: Su, Ruey-Chyi; Davie, James R

Keywords: Ace2 (Angiotensin-Converting Enzyme 2); Antiviral Response; Gene Regulation; Inflammation; Primary Human Cells; Sars-Cov-2 Spike Protein Variants

$431,000

Elucidating Wnt signalling mechanisms in pluripotent stem cells

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Doble, Bradley

Keywords: pluripotent stem cells; cell signalling; genome editing; micropatterning; intercellular communication; cell adhesion; organoids; cellular differentiation; cell fate determination; transcriptional regulation

$192,000

Novel therapeutic targets for Group 3 medulloblastoma stem cells

Co-investigatorCIHR2020Project Grant

Principal investigators: Werbowetski-Ogilvie, Tamra E

Keywords: Animal Models; Cancer Stem Cells; Lineage Tracing; Medulloblastoma; Mtor Signaling; Otx2; Pax Genes; Pediatric Cancer; Single Cell Rna Sequencing

$1,208,700

CANADA RESEARCH CHAIRHOLDER/TITULAIRE DES CHAIRES DE RECERCHE DU CANADA

Nominated PICIHR2011Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Doble, Bradley W

Keywords: Crc

$500,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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