Faculty profile
Tamra Werbowetski-Ogilvie
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Research
Latest papers
Embryonic Stem Cell Models of Human Brain Tumors.
Methods in molecular biology (Clifton, N.J.) · 2025 · senior author
OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells.
Disease models & mechanisms · 2015 · senior author
Latest funding
- $956,250
Taking down the 'undruggable' oncogene: therapeutic implications for novel mechanism-based targeting of MYC
CIHR · 2021 · Co-investigator
- $25,000
Prize - 202109PJT - Taking down the 'undruggable' oncogene: therapeutic implications for novel mechanism-based targeting of MYC
CIHR · 2021 · Co-investigator
- $1,208,700
Novel therapeutic targets for Group 3 medulloblastoma stem cells
CIHR · 2020 · Nominated PI
2 publications.
Embryonic Stem Cell Models of Human Brain Tumors.
Morrison LC, Tatari N, Werbowetski-Ogilvie T
OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells.
Kaur R, Aiken C, Morrison LC, Rao R, Del Bigio MR, Rampalli S, Werbowetski-Ogilvie T
Taking down the 'undruggable' oncogene: therapeutic implications for novel mechanism-based targeting of MYC
Principal investigators: Sharif, Tanveer
Keywords: Medulloblastoma; Metabolism; Myc; Oncogenes; Precision-Medicine
Prize - 202109PJT - Taking down the 'undruggable' oncogene: therapeutic implications for novel mechanism-based targeting of MYC
Principal investigators: Sharif, Tanveer
Keywords: Medulloblastoma; Metabolism; Myc; Oncogenes; Precision-Medicine
Novel therapeutic targets for Group 3 medulloblastoma stem cells
Principal investigators: Werbowetski-Ogilvie, Tamra E
Keywords: Animal Models; Cancer Stem Cells; Lineage Tracing; Medulloblastoma; Mtor Signaling; Otx2; Pax Genes; Pediatric Cancer; Single Cell Rna Sequencing
Tackling Childhood Brain Cancer at the root to improve survival and quality of life
Principal investigators: Taylor, Michael D
Keywords: Data Portal; Human Brain Development; Pediatric Brain Tumours
Characterization of novel OTX2-semaphorin gene signaling pathways regulating the "grow and go" arms of highly aggressive medulloblastomas
Principal investigators: Werbowetski-Ogilvie, Tamra E
Keywords: Animal Models; Cell Culture; Differentiation; Medulloblastoma; Otx2; Pediatric Brain Tumors; Self-Renewal; Semaphorin; Stem Cells
Targeting the regulation of subtypes of autophagy in cell survival and death to develop novel treatment strategies for glioblastoma.
Principal investigators: Gibson, Spencer B
Keywords: Autophagy; Cell Death; Cell Survival; Glioblastoma; Signal Transduction
CRC Tier 2
Principal investigators: Werbowetski-Ogilvie, Tamra E
Keywords: Crc
Investigating the role of Lin28A in human embryonic neural lineage function
Principal investigators: WerbowetskiOgilvie, Tamra
Functional characterization of novel biomarkers for subtype-specific medulloblastoma cell phenotypes
Principal investigators: Werbowetski-Ogilvie, Tamra E
Keywords: Cancer Progression Biomarkers; Cell Motility; Cell Sorting; Cell Surface Marker Screening; Flow Cytometry; Medulloblastoma; Pediatric Brain Tumors; Self-Renewal; Xenograft Models
CRC Tier 2
Principal investigators: Werbowetski-Ogilvie, Tamra E
Keywords: Chairs
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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