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Research
Latest papers
Lithium attenuates HIV-1 latency reversal in an autophagy-independent way.
iScience · 2025
Expansion of genital Tregs reduces neutrophil influx and maintains mucosal barrier integrity during inflammatory bacteria challenge.
Mucosal immunology · 2025
Effects of anesthesia modality on plasma proteomics and biomarkers of inflammation and vascular injury: an exploratory analysis.
Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025
Latest funding
- $20,000
38th Annual Canadian Society of Immunology (CSI) 2026 meeting
CIHR · 2025 · Nominated PI
- $1,139,850
Role of mucosal neutrophils in driving HIV/HPV infection and disease progression
CIHR · 2024 · Nominated PI
- $200,000
Evaluation of IFN-lambda as a novel antiviral therapeutic for genital HPV and HSV-2 infection in vivo
CIHR · 2024 · Nominated PI
3 publications.
Lithium attenuates HIV-1 latency reversal in an autophagy-independent way.
Abdalla AL, Guajardo-Contreras G, Chau BA, Niu M, Murooka T, Mouland AJ
Expansion of genital Tregs reduces neutrophil influx and maintains mucosal barrier integrity during inflammatory bacteria challenge.
Nuhu F, Costa-Fujishima M, Gavino C, Ssemaganda A, Verdipanah M, Jahan N, Murooka T, McKinnon LR
Effects of anesthesia modality on plasma proteomics and biomarkers of inflammation and vascular injury: an exploratory analysis.
Wiebe N, Spicer V, Sontag D, Lao Y, Erickson D, Halayko AJ, Murooka T, Gounni AS, Zeiler FA, Zahedi RP, Funk D, Mendelson AA
38th Annual Canadian Society of Immunology (CSI) 2026 meeting
Principal investigators: Murooka, Thomas T; Arsenio, Janilyn; Banerji, Versha; Ghia, Jean-Eric; Santer, Deanna; Su, Ruey-Chyi; Tremblay, Cedric S
Keywords: Autoimmune-Related Diseases; Cancer Immunology; Host-Pathogen Interactions; Immunology; Infectious Disease; Vaccines And Immunotherapies
Role of mucosal neutrophils in driving HIV/HPV infection and disease progression
Principal investigators: Murooka, Thomas T
Keywords: Bacterial Vaginosis; Hiv-1; Inflammation; Microscopy; Mouse Models Of Infection; Neutrophils; Papillmovirus; T Cells; Vaginal Mucosa
Evaluation of IFN-lambda as a novel antiviral therapeutic for genital HPV and HSV-2 infection in vivo
Principal investigators: Murooka, Thomas T; Ashkar, Ali A; Santer, Deanna
Keywords: Female Genital Tract; Herpes Simplex Virus (Hsv); Human Papillomavirus (Hpv); Immune Activation; Inflammation; Innate Immunity; Interferon-Lambda; Mouse Models Of Infection; Vaginal Epithelial Barrier; Virus Replication
Immunopathology of papillomavirus:bacterial co-infections in the female genital tract
Principal investigators: Murooka, Thomas T
Keywords: Cancer Formation; Mouse Model; Mucosal Immunology; Multiplex Tissue Imaging; Neutrophils; Papillomavirus; Vaginal Microbiome; Viral Infection
Understanding the cellular mechanisms that drive clonal T cell expansion of the HIV reservoir
Principal investigators: Murooka, Thomas T
Keywords: Antigen Presentation; Cell Migration; Dendritic Cells; Flourescent Proteins; Hiv Latency; Hiv Reservoir; Hiv-1; Humanized Mouse Models; Microscopy; T Cells
Regulatory T cells and the control of female genital inflammation: relevance for HIV prevention
Principal investigators: Mckinnon, Lyle R
Keywords: Female Genital Tract; Hiv; Inflammation; Mucosal; Prevention; Regulatory T Cells; Transmission
Subsets of subsets: investigating Th17 pathways in inflammatory bowel disease and HIV
Principal investigators: Mckinnon, Lyle R; Arsenio, Janilyn; Murooka, Thomas T
Keywords: Cd4+ T Cells; Cell-Mediated Immunity; Cytokines; Gastrointestinal; Hiv; Inflammatory Bowel Disease; Th17 Cells; Vaginal
Regulatory T cells and the control of female genital inflammation: relevance for HIV prevention
Principal investigators: Mckinnon, Lyle R
Keywords: Female Genital Tract; Hiv; Inflammation; Mucosal; Prevention; Regulatory T Cells; Transmission
Prize - 202109PJT - Regulatory T cells and the control of female genital inflammation: relevance for HIV prevention
Principal investigators: Mckinnon, Lyle R
Keywords: Female Genital Tract; Hiv; Inflammation; Mucosal; Prevention; Regulatory T Cells; Transmission
Regulatory T cells and the control of female genital inflammation: relevance for HIV prevention
Principal investigators: Mckinnon, Lyle R
Keywords: Female Genital Tract; Hiv; Inflammation; Mucosal; Prevention; Regulatory T Cells; Transmission
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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