Xi Yang, University of Manitoba

Research

Host Defense Immune Responses Infectious Diseases Medical Microbiology Chlamydia Trachomatis Dc-Targeting Vaccine Technology Multivalent Rvsv Vaccine Neutralizing Antibodies

Latest papers

Oncoprotein SND1-enriched exosomes facilitate melanoma lung metastasis by regulating CD47-SIRPα-mediated macrophage reprogramming.
Cancer letters · 2025
NK Cells Modulate Dendritic Cell (DC) Signaling Pathways and DC Recruitment in Chlamydial Infection.
International journal of molecular sciences · 2025 · senior author
Enhancement of Macrophage Immunity against Chlamydial Infection by Natural Killer T Cells.
Cells · 2024 · senior author

All 77 publications

Latest funding

Development of a multivalent rVSV vaccine against different Chlamydia trachomatis urogenital infections
CIHR · 2023 · Principal investigator
$450,000
Linkage between innate and adaptive immunity in chlamydial infection
CIHR · 2013 · Nominated PI
$767,307
Linkage between innate and adaptive immunity in chlamydial infection
CIHR · 2012 · Nominated PI
$100,000

All 6 grants and awards

77 publications.

01

Oncoprotein SND1-enriched exosomes facilitate melanoma lung metastasis by regulating CD47-SIRPα-mediated macrophage reprogramming.

Chen Y, Wang X, Li H, Zhang Z, Gao Y, Ge L, Xin L, Gao X, Shi L, Hao J, Yao Z, Chen J, Yang X, Yang J

Cancer letters2025

DOI: 10.1016/j.canlet.2025.218037 PMID: 41015268

02

NK Cells Modulate Dendritic Cell (DC) Signaling Pathways and DC Recruitment in Chlamydial Infection.

Wang X, Zhang C, Zhang Y, Wang S, Thomas R, Yang X

International journal of molecular sciences2025Senior author

DOI: 10.3390/ijms26083769 PMID: 40332391

03

Enhancement of Macrophage Immunity against Chlamydial Infection by Natural Killer T Cells.

Peng Y, Qiao S, Wang H, Shekhar S, Wang S, Yang J, Fan Y, Yang X

Cells2024Senior author

DOI: 10.3390/cells13020133 PMID: 38247825

04

IFNγ-Producing B Cells Play a Regulating Role in Infection-Mediated Inhibition of Allergy.

Qiao S, Peng Y, Zhang C, Thomas R, Wang S, Yang X

Biology2023Senior author

DOI: 10.3390/biology12091259 PMID: 37759658

05

Semaphorins in immune cell function, inflammatory and infectious diseases.

Thomas R, Yang X

Current research in immunology2023Senior author

DOI: 10.1016/j.crimmu.2023.100060 PMID: 37645659

06

Th17/Treg Imbalance: Implications in Lung Inflammatory Diseases.

Thomas R, Qiao S, Yang X

International journal of molecular sciences2023Senior author

DOI: 10.3390/ijms24054865 PMID: 36902294

07

Bidirectional Functional Effects of Staphylococcus on Carcinogenesis.

Wei Y, Sandhu E, Yang X, Yang J, Ren Y, Gao X

Microorganisms2022

DOI: 10.3390/microorganisms10122353 PMID: 36557606

08

Exogenous Semaphorin 3E treatment protects against chlamydial lung infection in mice.

Thomas R, Wang S, Rashu R, Peng Y, Gounni AS, Yang X

Frontiers in immunology2022Senior author

DOI: 10.3389/fimmu.2022.882412 PMID: 35983029

09

Cross Talk Between Natural Killer T and Dendritic Cells and Its Impact on T Cell Responses in Infections.

Zhao L, Yang X

Frontiers in immunology2022Senior author

DOI: 10.3389/fimmu.2022.837767 PMID: 35185930

10

Natural Killer Cells Regulate Pulmonary Macrophages Polarization in Host Defense Against Chlamydial Respiratory Infection.

Zhao L, Li J, Zhou X, Pan Q, Zhao W, Yang X, Wang H

Frontiers in cellular and infection microbiology2021

DOI: 10.3389/fcimb.2021.775663 PMID: 35059323

Development of a multivalent rVSV vaccine against different Chlamydia trachomatis urogenital infections

Principal investigatorCIHR2023Op. Gr.: STBBI Research in Canada: Beyond HIV/AIDS and Hepatitis C - Chlamydia

Principal investigators: Yao, Xiao-Jian; Yang, Xi

Keywords: Chlamydia Trachomatis; Dc-Targeting Vaccine Technology; Multivalent Rvsv Vaccine; Neutralizing Antibodies; Sexually Transmitted Infections; The Major Outer Membrane Protein; Urogenital Infections

$450,000