Faculty profile
Barbara Karten
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses may be missing. Find their university profile.
Research
Latest papers
NCK1 Modulates Neuronal Actin Dynamics and Promotes Dendritic Spine, Synapse, and Memory Formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
Measurement of Mitochondrial Cholesterol Import Using a Mitochondria-Targeted CYP11A1 Fusion Construct.
Methods in molecular biology (Clifton, N.J.) · 2017 · senior author
Mitochondrial cholesterol import.
Biochimica et biophysica acta. Molecular and cell biology of lipids · 2017 · senior author
Latest funding
- $140,000
Upgrade to Protein Imaging Suite
NSERC · 2021 · Co-investigator
- $149,999
High-throughput single-cell imaging flow cytometry platform
NSERC · 2019 · Co-investigator
- $252,000
Regulation of structural plasticity and actin cytoskeleton by plasma membrane cholesterol turnover in dendritic spines
NSERC · 2018 · Principal investigator
14 publications.
NCK1 Modulates Neuronal Actin Dynamics and Promotes Dendritic Spine, Synapse, and Memory Formation.
Diab AM, Wigerius M, Quinn DP, Qi J, Shahin I, Paffile J, Krueger K, Karten B, Krueger SR, Fawcett JP
Measurement of Mitochondrial Cholesterol Import Using a Mitochondria-Targeted CYP11A1 Fusion Construct.
Kennedy BE, Charman M, Karten B
Mitochondrial cholesterol import.
Elustondo P, Martin LA, Karten B
Meeting report from the 58th Annual Meeting of the CSMB: Lipids - the membrane and beyond.
Karten B, Rainey JK
Presymptomatic Alterations in Amino Acid Metabolism and DNA Methylation in the Cerebellum of a Murine Model of Niemann-Pick Type C Disease.
Kennedy BE, Hundert AS, Goguen D, Weaver IC, Karten B
Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function.
Martin LA, Kennedy BE, Karten B
Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin.
Vance JE, Karten B
Adaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells.
Kennedy BE, Madreiter CT, Vishnu N, Malli R, Graier WF, Karten B
Pre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brain.
Kennedy BE, LeBlanc VG, Mailman TM, Fice D, Burton I, Karakach TK, Karten B
Niemann-Pick Type C2 protein contributes to the transport of endosomal cholesterol to mitochondria without interacting with NPC1.
Kennedy BE, Charman M, Karten B
Upgrade to Protein Imaging Suite
Principal investigators: Marignani, Paola
High-throughput single-cell imaging flow cytometry platform
Principal investigators: Cheng, Zhenyu
Regulation of structural plasticity and actin cytoskeleton by plasma membrane cholesterol turnover in dendritic spines
Principal investigators: Karten, Barbara
Role of mitochondrial cholesterol homeostasis in brain energy metabolism and neuronal function
Principal investigators: Karten, Barbara
Keywords: Amino Acid Metabolism; Cholesterol Trafficking; Energy Metabolism; Mitochondrial Cholesterol; Niemann-Pick Type C Disease; Primary Neuron Culture; Synaptic Function
Multi-user fluorescence microscope for live cell imaging
Principal investigators: Duncan, Roy
Benchtop ultracentrifuge for molecular cell biology
Principal investigators: Duncan, Roy
Regulation of synapse formation and function by cholesterol
Principal investigators: Karten, Barbara
Mitochondrial dysfunction and brain energy metabolism in the pathogenesis of Niemann-Pick Type C disease
Principal investigators: Karten, Barbara
Keywords: Cholesterol Trafficking; Energy Metabolism; Mitochondrial Dysfunction; Neuronal Function; Niemann-Pick Type C Disease; Oxidative Stress
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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