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Research
Latest papers
Evaluation of an oral Beta-caryophyllene Indena Phytosome® for the treatment of pain and inflammation in interstitial cystitis.
Clinical hemorheology and microcirculation · 2026
Cannabidiol Reduces Systemic Immune Activation in Experimental Acute Lung Injury.
Cannabis and cannabinoid research · 2024
Amelioration of Dextran Sodium Sulfate-Induced Colitis in Mice through Oral Administration of Palmitoylethanolamide.
Biomedicines · 2024
Latest funding
- $623,476
The Serine Hydrolases: Positioned at the Axis of Endocannabinoid-Eicosanoid Signaling
CIHR · 2019 · Nominated PI
- $689,578
The ocular endocannabinoid system: Pharmacology of an endogenous lipid signaling system.
CIHR · 2014 · Nominated PI
- $175,000
THE ENDOTHELIN SYSTEM AND MYOGENIC TONE: G PROTEIN COUPLED RECEPTOR SIGNALING IN RESISTANCE ARTERIES OF THE CENTRAL NERVOUS SYSTEM
NSERC · 2014 · Principal investigator
7 publications.
Evaluation of an oral Beta-caryophyllene Indena Phytosome® for the treatment of pain and inflammation in interstitial cystitis.
White H, Dickson K, Scott C, Agonh DN, Cox A, Kelly M, Zhou J, Lehmann C
Cannabidiol Reduces Systemic Immune Activation in Experimental Acute Lung Injury.
Hall S, Faridi S, Trivedi P, Castonguay M, Kelly M, Zhou J, Lehmann C
Amelioration of Dextran Sodium Sulfate-Induced Colitis in Mice through Oral Administration of Palmitoylethanolamide.
Trivedi P, Myers T, Ray B, Allain M, Zhou J, Kelly M, Lehmann C
Antibacterial and Analgesic Properties of Beta-Caryophyllene in a Murine Urinary Tract Infection Model.
Dickson K, Scott C, White H, Zhou J, Kelly M, Lehmann C
Selective CB2 Receptor Agonist, HU-308, Reduces Systemic Inflammation in Endotoxin Model of Pneumonia-Induced Acute Lung Injury.
Hall S, Faridi S, Trivedi P, Sultana S, Ray B, Myers T, Euodia I, Vlatten D, Castonguay M, Zhou J, Kelly M, Lehmann C
Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators.
Garai S, Kulkarni PM, Schaffer PC, Leo LM, Brandt AL, Zagzoog A, Black T, Lin X, Hurst DP, Janero DR, Abood ME, Zimmowitch A, Straiker A, Pertwee RG, Kelly M, Szczesniak AM, Denovan-Wright EM, Mackie K, Hohmann AG, Reggio PH, Laprairie RB, Thakur GA
Experimental Cannabinoid 2 Receptor Activation by Phyto-Derived and Synthetic Cannabinoid Ligands in LPS-Induced Interstitial Cystitis in Mice.
Berger G, Arora N, Burkovskiy I, Xia Y, Chinnadurai A, Westhofen R, Hagn G, Cox A, Kelly M, Zhou J, Lehmann C
The Serine Hydrolases: Positioned at the Axis of Endocannabinoid-Eicosanoid Signaling
Principal investigators: Kelly, Melanie E
Keywords: Alpha Beta Hydroxylase Domain 6; Alpha/Beta Hydroxylase Domain 12; Central Nervous System; Eicosanoid; Endocannabinoid System; Monoacyl Glycerol Lipase; Neurodegeneration; Neuroinflammation; Retina; Serine Hydrolases
The ocular endocannabinoid system: Pharmacology of an endogenous lipid signaling system.
Principal investigators: Kelly, Melanie E
Keywords: Cannabinoids; Endocannabinoid System; G Protein Coupled Receptors; Inflammation; Intraocular Pressure; Lipid Signaling; Microvasculature; Neurodegeneration; Ocular; Retina
THE ENDOTHELIN SYSTEM AND MYOGENIC TONE: G PROTEIN COUPLED RECEPTOR SIGNALING IN RESISTANCE ARTERIES OF THE CENTRAL NERVOUS SYSTEM
Principal investigators: Kelly, Melanie
The microvasculature in the aging eye: a target for neuroprotection in age-related ocular disease
Principal investigators: Kelly, Melanie E
Keywords: Aging; Glaucoma; Microvasculature; Neuroprotection; Retina; Retinal Ischemia
Lipid signaling in the eye: Pharmacology of cannabinoid receptors and their ligands.
Principal investigators: Kelly, Melanie E
Keywords: Cell Signaling; Endocannabinoid System; Intraocular Pressure; Ocular Pharmacology; Receptors; Vasculature
Lipid signaling in the eye: Pharmacology of cannabinoid receptors and their ligands.
Principal investigators: Kelly, Melanie E
Keywords: Cell Signaling; Endocannabinoid System; Intraocular Pressure; Ocular Pharmacology; Receptors; Vasculature
Calcium signaling in retinal glia
Principal investigators: Kelly, Melanie
Liquid scintillation counter
Principal investigators: Blay, Jonathan
Regulation of ion channels and cell function in retinal glia and epithelial cells
Principal investigators: Kelly, Melanie
Regulation of function in retinal pigment epithelial and Müller cells
Principal investigators: Kelly, Melanie
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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