Jennifer Bruin

Genotoxic environmental chemicals as drivers of pancreatic islet mutagenesis and metabolic dysfunction

Principal investigators: Bruin, Jennifer E; Marchetti, Francesco; Yauk, Carole L

Keywords: Aryl Hydrocarbon Receptor; Dna Damage; Insulin Secretion; Islet Biology; Mutagenesis; Polycyclic Aromatic Hydrocarbons; Toxicology

Effects of genotoxic environmental chemicals on islets: role of the beta cell aryl hydrocarbon receptor

Principal investigators: Bruin, Jennifer E; Marchetti, Francesco; Yauk, Carole L

Keywords: Aryl Hydrocarbon Receptor; Dna Damage; Insulin Secretion; Islet Biology; Mutagenesis; Polycyclic Aromatic Hydrocarbonsc; Toxicology

Role of aryl hydrocarbon receptor in adaptation of beta cells to high fat diet feeding in mice

Principal investigators: Tubana-Dean, Shania

Keywords: Aryl Hydrocarbon Receptor; Diabetes Pathogenesis; Environmental Pollutants; Pancreas; Type 2 Diabetes

Investigating the impact of chemotherapeutic agents on mouse and human pancreatic islets

Principal investigators: Grieco-St-Pierre, Lili

Keywords: Beta Cells; Cancer; Chemotherapy; Diabetes; Insulin; Islets

Canadian Islet Research and Training Network - Réseau de Recherche et Formation sur les Ilots du Canada (CIRTN-R2FIC) National Meeting

Principal investigators: Bruin, Jennifer E; Fullerton, Morgan D

Keywords: Insulin; Islet Biology; Metabolism; Nutrition; Stem Cells; Type 1 Diabetes; Type 2 Diabetes

Determining the effects of per- and polyfluoroalkyl substances (PFAS) on islet function and transcriptome

Principal investigators: van Zyl, Erin P

Keywords: Beta Cell Function; Diabetes; Environmental Pollutants; Human Islets; Insulin Secretion; Metabolic Stress; Per- And Polyfluorinated Substances (Pfas); Tempo-Seq; Toxicology; Transcriptomics

Examining the Impact of Chemotherapeutic Agents on Beta Cell Function and Health in Mouse and Human Islets

Principal investigators: Basu, Lahari

Keywords: Beta Cell Function; Chemotherapy; Diabetes; Dna Damage; Electrophysiological Function; Insulin Secretion; Metabolism; Mitochondrial Function; Mouse Model; Pancreatic Islets

Updated Infrastructure for the Carleton University Biomolecular Radiation Facility

Principal investigators: Bruin, Jennifer

Canadian Islet Research and Training Network - Réseau de Recherche et Formation sur les Ilots du Canada (CIRTN-R2FIC)

Principal investigators: MacDonald, Patrick PE

Effects of fluorinated pollutants on maternal metabolic health: a translational toxicology approach

Principal investigators: Bruin, Jennifer E; Fisher, Mandy; Mennigen, Jan A; Yauk, Carole L

Keywords: Environmental Contamants; Epidemiology; Islets; Mouse Models; Pfas; Toxicology; Type 2 Diabetes; Zebrafish