Faculty profile
Charles Graham
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Research
Latest papers
DNA damage repair gene mutations and their association with tumor immune regulatory gene expression in muscle invasive bladder cancer subtypes.
Journal for immunotherapy of cancer · 2019
Mechanisms Of Hypoxia-Induced Immune Escape In Cancer And Their Regulation By Nitric Oxide.
Redox biology · 2015 · first author
Latest funding
- $20,000
American Society for Reproductive Immunology 2025 meeting
CIHR · 2024 · Principal investigator
- $1,086,300
Role of trained immunity in the response to BCG immunotherapy of bladder cancer
CIHR · 2020 · Nominated PI
- $1,036,575
Effect of aberrant inflammation during pregnancy on subsequent risk of cardiovascular disease in mothers and their offspring
CIHR · 2017 · Nominated PI
2 publications.
DNA damage repair gene mutations and their association with tumor immune regulatory gene expression in muscle invasive bladder cancer subtypes.
Vidotto T, Nersesian S, Graham C, Siemens DR, Koti M
Mechanisms Of Hypoxia-Induced Immune Escape In Cancer And Their Regulation By Nitric Oxide.
Graham C, Barsoum I, Kim J, Black M, Siemens RD
American Society for Reproductive Immunology 2025 meeting
Principal investigators: Tayade, Chandrakant; Girard, Sylvie; Graham, Charles H
Keywords: Fertility; Immunology; Infection; Pregnancy; Reproduction; Reproductive Disorders; Reproductive Immunology
Role of trained immunity in the response to BCG immunotherapy of bladder cancer
Principal investigators: Graham, Charles H; Siemens, Robert
Keywords: Adaptive Immunity; Bladder Cancer; Immunotherapy; Innate Immunity
Effect of aberrant inflammation during pregnancy on subsequent risk of cardiovascular disease in mothers and their offspring
Principal investigators: Graham, Charles H
Keywords: Cardiovascular Disease; Developmental Origins Of Disease; Fetal Growth Restriction; Pre-Eclampsia; Pregnancy
Role of the Programmed Death Ligand 1 (PD-L1) immune checkpoint in the acquisition of malignant phenotypes in tumour cells
Principal investigators: Minassian, Lori
Keywords: Cancer; Drug Resistance; Immune Checkpoint; Malignancy; Metastasis
Acquisition of malignant phenotypes in tumour cells mediated by the PD-1/PD-L1 immune checkpoint
Principal investigators: Graham, Charles H
Keywords: Cancer; Drug Resistance; Immune Checkpoint; Metastasis
Third International Workshop on Nitric Oxide in Cancer Therapy
Principal investigators: Graham, Charles H
Keywords: Cancer; International Workshop; Nitric Oxide
Role of maternal inflammation in the pathophysiology of intrauterine growth restriction and pre-eclampsia
Principal investigators: Graham, Charles H
Keywords: Blood Flow; Immunology; Placenta; Pregnancy; Pregnancy Complications; Rat Model
Mechanisms of hypoxia-induced immune escape in cancer and their regulation by nitric oxide
Principal investigators: Graham, Charles H
Keywords: Cancer; Cell Biology; Hypoxia; Immune Escape; Immunology; Nitric Oxide
Role of inflammation in the pathophysiology of intrauterine growth restriction and pre-eclampsia
Principal investigators: Cotechini, Tiziana
Keywords: Doppler Ultrasound; Haemostasis; Hemodynamics; Inflammation; Intrauterine Growth Restriction; Intravital Microscopy; Pathophysiolgy; Pre-Eclampsia; Pregnancy; Radiotelemetry
Nitric oxide-mediated regulation of hypoxia-induced stem cell-like phenotypes in cancer cells
Principal investigators: Smallwood, Chelsea A
Keywords: Cancer; Cancer Stem Cell; Cd133 Marker; Cd44; Flow Cytometry; Hypoxia; Nitric Oxide; Quantitative Pcr; Western Blot
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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