Faculty profile
Mark Ormiston
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Research
Latest funding
- $120,000
Investigating the role for natural killer cell TGF-beta signaling in cardiopulmonary development and the pathogenesis of Bronchopulmonary Dysplasia
CIHR · 2025 · Supervisor
- $105,000
Examining the impact of endothelial BMPR2 loss on the transcriptional and functional response to BMP9 in pulmonary arterial hypertension
CIHR · 2021 · Supervisor
- $787,950
Targeting bone morphogenetic protein-9 as an angioproliferative switch in pulmonary arterial hypertension
CIHR · 2021 · Nominated PI
Investigating the role for natural killer cell TGF-beta signaling in cardiopulmonary development and the pathogenesis of Bronchopulmonary Dysplasia
Principal investigators: Gainer, Declan
Keywords: Bronchopulmonary Dysplasia; Cellular Senescence; Endothelial Cells; Flow Cytometry; Immunohistochemistry; Immunotherapies; Lung Development; Natural Killer Cells; Single Cell Rna Sequencing; Transforming Growth Factor-Beta
Examining the impact of endothelial BMPR2 loss on the transcriptional and functional response to BMP9 in pulmonary arterial hypertension
Principal investigators: VandenBroek, Michael M
Keywords: Animal Models Of Disease; Bone Morphogenetic Proteins; Endothelial Cell Biology; Pulmonary Arterial Hypertension; Transcriptomics; Vascular Remodeling
Targeting bone morphogenetic protein-9 as an angioproliferative switch in pulmonary arterial hypertension
Principal investigators: Ormiston, Mark L
Keywords: Angiogenesis; Bone Morphogenetic Proteins; Conditional Knockout Mouse Models; Endothelial Cells; Pulmonary Arterial Hypertension; Transcriptomics; Type Ii Bone Morphogenetic Protein Receptor (Bmpr2)
Examining the role for natural killer cell TGFb signaling in pulmonary vascular development and the pathogenesis of pulmonary hypertension
Principal investigators: Ormiston, Mark L
Keywords: Conditional Knockout Mouse Models; Immunity; Natural Killer Cells; Pulmonary Arterial Hypertension; Pulmonary Vascular Development; Single Cell Rna Sequencing; Transforming Growth Factor-B
Canada Research Chairs - Tier 2
Principal investigators: Ormiston, Mark L
Keywords: Crc
Neuro-immune control of postoperative pain via CCL22:CCR4 signaling
Principal investigators: Ghasemlou, Nader
Keywords: Behavioural Assays; Cytokines; Dendritic Cells; Electrophysiology; Immunology; Neuroinflammation; Neuroscience; Pain
Neuro-immune control of postoperative pain via CCL22:CCR4 signalling
Principal investigators: Ghasemlou, Nader
Keywords: Behavioural Assays; Cytokines; Dendritic Cells; Electrophysiology; Immunology; Inflammation; Neuroscience; Pain
A novel therapeutic approach to pulmonary arterial hypertension - targeting natural killer cells through the interleukin-15 and transforming growth factor-beta pathways.
Principal investigators: Ratsep, Matthew T
Keywords: Blood Pressure; Cardiac Catheterization; Cardiovascular; Cell Biology; Cell Therapy; Endothelium; Genetics; Mouse Models; Natural Killer Cells; Pulmonary Hypertension
Manipulating IL-15 and TGFb signaling augments Natural Killer cell homeostasis and protects from experimental pulmonary arterial hypertension
Principal investigators: Ratsep, Matthew T
Keywords: Blood Pressure; Cardiac Catheterization; Cardiovascular; Cell Therapy; Echocardiography; Endothelium; Flow Cytometry; Natural Killer Cells; Pulmonary Arterial Hypertension; Rodent Models
Cellular and molecular mechanisms of Natural Killer cell-mediated vascular remodeling in pulmonary arterial hypertension
Principal investigators: Ormiston, Mark L
Keywords: Angiogenesis; Cardiopulmonary Phenotyping In Mice; Cardiovascular Immunology; Cytof; Natural Killer Cells; Pulmonary Arterial Hypertension; Rna-Seq
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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