Faculty profile
Roberto Botelho
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Latest papers
Aluminum hydroxide adjuvant diverts the uptake and trafficking of genetically detoxified pertussis toxin to lysosomes in macrophages.
Molecular microbiology · 2022
Latest funding
- $1,071,000
The functions and mechanisms of lysosome remodelling during immuno-stimulation of antigen-presenting cells
CIHR · 2024 · Nominated PI
- $150,000
A Dual Camera Acquisition-Spinning Disc Confocal Microscope System to Study Cellular Dynamics
NSERC · 2023 · Principal investigator
- $837,676
Understanding the molecular processes governing phagocytic capacity and appetite, and phagosome resolution in macrophages
CIHR · 2022 · Nominated PI
1 publications.
Aluminum hydroxide adjuvant diverts the uptake and trafficking of genetically detoxified pertussis toxin to lysosomes in macrophages.
Jaldin-Fincati J, Moussaoui S, Gimenez MC, Ho CY, Lancaster CE, Botelho R, Ausar F, Brookes R, Terebiznik M
The functions and mechanisms of lysosome remodelling during immuno-stimulation of antigen-presenting cells
Principal investigators: Botelho, Roberto J
Keywords: Adaptation; Antigen Presentation; Dendritic Cells; Innate Immunity; Lysosomes; Macrophages; Modelling; Mrna-Lipid Nanoparticles; Signalling; Vaccines
A Dual Camera Acquisition-Spinning Disc Confocal Microscope System to Study Cellular Dynamics
Principal investigators: Botelho, Roberto
Understanding the molecular processes governing phagocytic capacity and appetite, and phagosome resolution in macrophages
Principal investigators: Botelho, Roberto J
Keywords: Adaptation; Biophysical; Clathrin; Immunity; Infection; Lysosomes; Macrophages; Membranes; Phagocytosis; Phagosomes
COVID-19: Ultrasound-microbubble targeted delivery of immuno-modulatory therapeutics to treat COVID-19_x000d_ _x000d_ _x000d_ _x000d_
Principal investigators: Botelho, Roberto
Regulation and Function of Phosphoinositide Lipid Signals
Principal investigators: Botelho, Roberto
Dynamic Imaging: high resolution, long-term approaches to molecular mechanisms
Principal investigators: Sabatinos, Sarah
Translation regulation and lysosome expansion in immune function
Principal investigators: Botelho, Roberto J
Keywords: Antigen Presenting Cells; Dendritic Cells; Imaging; Lysosomes; Macrophages; Systems Biology; Trafficking; Translation
Canada Research Chair - Tier 2
Principal investigators: Botelho, Roberto J
Keywords: Crc
Identification and the role of stress-activated molecular pathways in cell adaptation during**microbubble-coupled sonoporation
Principal investigators: Botelho, Roberto
Organelle Dynamics and Systems Biology Joint Scientific Sessions
Principal investigators: Antonescu, Costin N
Keywords: Cancer; Cell Biology; Systems Biology
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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