Jeremy Simpson, University of Guelph

Research

Cell Signaling Diastolic Dysfunction Fibrosis Heart Failure Inflammation Vertebrates - Rats Hypertrophy

Latest papers

Heart ventricle regeneration in the lizard Eublepharis macularius, the leopard gecko.
NPJ Regenerative medicine · 2026
Importance of assessing biomarkers and physiological parameters of anemia-induced tissue hypoxia in the perioperative period.
Brazilian journal of anesthesiology (Elsevier) · 2023
Experimentally induced spine osteoarthritis in rats leads to neurogenic inflammation within neurosegmentally linked myotomes.
Experimental gerontology · 2021

All 6 publications

Latest funding

Advanced High-Resolution Imaging for Muscle and Brain Research
NSERC · 2025 · Principal investigator
$150,000
Defining the distinct and progressive sex differences of a novel experimental model of pure diastolic dysfunction
CIHR · 2019 · Nominated PI
$753,526
homeostatic regulation of erythrocytes
NSERC · 2018 · Principal investigator
$174,000

All 11 grants and awards

6 publications.

01

Heart ventricle regeneration in the lizard Eublepharis macularius, the leopard gecko.

Jacyniak K, Williams CJA, Beaufrère H, Simpson J, Huang GN, Chen X, Vickaryous MK

NPJ Regenerative medicine2026

DOI: 10.1038/s41536-026-00469-8 PMID: 41986369

02

Importance of assessing biomarkers and physiological parameters of anemia-induced tissue hypoxia in the perioperative period.

Chin K, Joo H, Jiang H, Lin C, Savinova I, Joo S, Alli A, Sklar MC, Papa F, Simpson J, Baker AJ, Mazer CD, Darrah W, Hare GMT

Brazilian journal of anesthesiology (Elsevier)2023

DOI: 10.1016/j.bjane.2022.10.004 PMID: 36377057

03

Experimentally induced spine osteoarthritis in rats leads to neurogenic inflammation within neurosegmentally linked myotomes.

Duarte FCK, Hurtig M, Clark A, Brown S, Simpson J, Srbely J

Experimental gerontology2021

DOI: 10.1016/j.exger.2021.111311 PMID: 33744392

04

Association between naturally occurring spine osteoarthritis in geriatric rats and neurogenic inflammation within neurosegmentally linked skeletal muscle.

Duarte FCK, Hurtig M, Clark A, Simpson J, Srbely JZ

Experimental gerontology2019

DOI: 10.1016/j.exger.2019.01.002 PMID: 30615897

05

The Effect of Anthocyanin-Rich Purple Vegetable Diets on Metabolic Syndrome in Obese Zucker Rats.

Ayoub HM, McDonald MR, Sullivan JA, Tsao R, Platt M, Simpson J, Meckling KA

Journal of medicinal food2017

DOI: 10.1089/jmf.2017.0025 PMID: 28956702

06

Day-night dependence of gene expression and inflammatory responses in the remodeling murine heart post-myocardial infarction.

Bennardo M, Alibhai F, Tsimakouridze E, Chinnappareddy N, Podobed P, Reitz C, Pyle WG, Simpson J, Martino TA

American journal of physiology. Regulatory, integrative and comparative physiology2016

DOI: 10.1152/ajpregu.00200.2016 PMID: 27733386

Advanced High-Resolution Imaging for Muscle and Brain Research

Principal investigatorNSERC2025Research Tools and Instruments

Principal investigators: Simpson, Jeremy

Keywords: cardiac physiology; cardiogenesis; advanced non-invasive imaging; integrative mammalian physiology; sex differences; hqp training; metabolism; endocrine; heart-brain interactions; mitochondria

$150,000

Defining the distinct and progressive sex differences of a novel experimental model of pure diastolic dysfunction

Nominated PICIHR2019Project Grant

Principal investigators: Simpson, Jeremy A; Brunt, Keith R

Keywords: Cell Signaling; Diastolic Dysfunction; Fibrosis; Heart Failure; Inflammation; Vertebrates - Rats

$753,526

homeostatic regulation of erythrocytes

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Simpson, Jeremy

$174,000

Defining the distinct and progressive sex differences of a novel experimental model of pure diastolic dysfunction

Nominated PICIHR2018Project Grant - PA: Sex, Gender & Health Research - Integration & Innovation

Principal investigators: Simpson, Jeremy A; Brunt, Keith R

Keywords: Cell Signaling; Diastolic Dysfunction; Fibrosis; Heart Failure; Hypertrophy; Inflammation; Vertebrates - Rats

$100,000

Muscle fibre mechanical testing apparatus

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Brown, Stephen

$47,099

Real Time Polymerase Chain Reaction Machine

Co-investigatorNSERC2013Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Wright, David

$23,639

MODERN BIOBUBBLE UNITS TO SUPPORT BASIC RESEARCH USING ANIMAL MODELS

Co-investigatorNSERC2012Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Ma, David

$119,248

Department Core Facility Plate Reader

Co-investigatorNSERC2012Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Lindinger, Michael

$56,000

Post-translational modification of myofilament proteins in the regulation of skeletal muscle contraction.

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Simpson, Jeremy

$174,000

Myocardial Production of Erythropoietin and hemoglobin variants

Nominated PICIHR2010Operating Grant

Principal investigators: Simpson, Jeremy A

Keywords: Cardiac; Cytokines; Erythropoietin; Heart Failure; Hemoglobin; Rodent

$315,790

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2025

Subject: Prospective PhD student: Cell Signaling Dear Professor Simpson, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Heart ventricle regeneration in the lizard Eublepharis macularius, the leopard gecko." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Advanced High-Resolution Imaging for Muscle and Brain Research" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]