Faculty profile

Alexander Mackenzie

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ProfessorPediatricsUniversity of Ottawa

Alexander Mackenzie

Professor

Pediatrics

Faculty of Medicine

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
1 publication in the last five years, latest in 2025.
Principal investigator on 3 research grants (3 CIHR), most recently in 2018.
Supervised 1 trainee who won CIHR awards, most recently in 2016.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Cell Phenotype Drug Screen Muscular Dystrophy Cognitive Behavioural Therapy (Cbt)Myotonic Dystrophy Type 1 (Dm1)Systems Biology

Latest papers

Development of a riboflavin-responsive model of riboflavin transporter deficiency in zebrafish.
Human molecular genetics · 2025
Lactobacillus plantarum 299v Prevents Caspase-Dependent Apoptosis In Vitro.
Probiotics and antimicrobial proteins · 2011
Pulse probiotic administration induces repeated small intestinal Muc3 expression in rats.
Pediatric research · 2011

All 3 publications

Latest funding

NMD4C: the neuromuscular network for Canada
CIHR · 2023 · Co-investigator
$1,000,000
Accelerating drug repurposing for rare neurological, neurometabolic and neuromuscular diseases by exploiting SIMilarities in clinical and molecular PATHology (SIMPATHIC)
SSHRC · 2022 · Co-investigator
$490,178
An innovative registry-based trials platform to improve clinical care, outcomes, and health policy for children with treatable rare diseases
CIHR · 2019 · Co-investigator
$2,754,009

All 10 grants and awards

NMD4C: the neuromuscular network for Canada

Co-investigatorCIHR2023Network Gr. in Skin Health, Bone Health, and Muscular Dyst. - Muscular Dystrophy

Principal investigators: Lochmüller, Hanns; Osman, Homira; Brais, Bernard; Campbell, Craig Gordon N; Chang, Natasha C; Dowling, James; Gagnon, Cynthia; Gonorazky, Hernan D; Hodgkinson, Victoria; Karamchandani, Jason; Korngut, Lawrence W; Kothary, Rashmi K; Mah, Jean K; O'Connell, Colleen; Patten, Kessen; Rossi, Fabio M; Schellenberg, Kerri; Selby, Kathryn A; Warman Chardon, Jodi

Keywords: Clinical Trial Networks; Networks; Neuromuscular Disease; Open Science; Patient Partnerships; Preclinical Research Resources; Training And Education; Translational Research

$1,000,000

Accelerating drug repurposing for rare neurological, neurometabolic and neuromuscular diseases by exploiting SIMilarities in clinical and molecular PATHology (SIMPATHIC)

Co-investigatorSSHRC2022New Frontiers in Research Fund - Global Platforms

Principal investigators: Lochmüller, Hanns

Keywords: Neuromuscular Diseases; Drug Repurposing; Clinical Trials; Rare Disease; IPSc; Cellular Models; Drug Screens; Basket Trials

$490,178

An innovative registry-based trials platform to improve clinical care, outcomes, and health policy for children with treatable rare diseases

Co-investigatorCIHR2019Operating Grant: SPOR Innovative Clinical Trial Multi-Year Grant

Principal investigators: Potter, Elizabeth K; McCabe, Christopher; Smith, Maureen M; Binik, Ariella; Chakraborty, Pranesh K; Inbar-Feigenberg, Michal; Mitchell, John J; Offringa, Martin; Oskoui, Maryam; Stockler, Sylvia

Keywords: Comparative Effectiveness; Core Outcomes; Genetic Disease; Innovative Clinical Trial; Orphan Therapy; Patient Partnership; Patient-Oriented Outcomes; Pediatrics; Rare Disease; Registry-Based Randomized Trial

$2,754,009

Pharmacologic and RNAi Screens for Myotonic Dystrophy Type 1 foci modulators; towards Novel DM1 therapeutic approaches

Nominated PICIHR2018Project Grant

Principal investigators: Mackenzie, Alexander E; Jasmin, Bernard J

Keywords: Cell Phenotype; Drug Screen; Muscular Dystrophy

$481,950

Recognition and Validation of Druggable Targets from the Response to Cognitive Behaviour Therapy in Myotonic Dystrophy type 1 patients from Integrated -Omics Networks

Nominated PICIHR2018Team Grant: E-Rare Joint Transnational Call

Principal investigators: Mackenzie, Alexander E

Keywords: Cognitive Behavioural Therapy (Cbt); Myotonic Dystrophy Type 1 (Dm1); Systems Biology

$75,000

Catalyzing registry-based randomized comparative effectiveness trials for inherited metabolic diseases in children: establishing a core outcome set and data collection tools

Co-investigatorCIHR2016Catalyst Grant: SPOR Innovative Clinical Trials (iCT)

Principal investigators: Potter, Elizabeth K; Clifford, Tammy J; Pallone, Nicole; Stockler, Sylvia

Keywords: Inherited Metabolic Disease; Pediatrics; Pragmatic Trial; Rare Disease; Registry; Registry-Based Randomized Trial

$100,000

Zebrafish models for pyridoxine dependent epilepsy research; drug discovery and pre-clinical validation

SupervisorCIHR2016CIHR Fellowship

Principal investigators: Agostinho Pena, Izabella

Keywords: Genetics; Lysine Degradation; Molecular Biology; Pyridoxine Dependent Epilepsy; Rare Diseases; Zebrafish Models

$135,000

Enhanced CARE for RARE Genetic Diseases in Canada

Co-investigatorCIHR2012Genomics and Personalized Health

Principal investigators: Boycott, Kym M

Keywords: Gene Identification; Health Economics; Molecular Diagnostics; Rare Disease Treatment; Rare Diseases

$2,500,000

Preclinical assessment of clinic ready agents for the treatment of muscular dystrophy and spinal muscular atrophy

Nominated PICIHR2011Operating Grant - Priority Announcement: Neuromuscular Research

Principal investigators: Mackenzie, Alexander E

Keywords: Muscular Dystrophy; Neuromuscular Disorders; Pharmacologic Gene Modulation; Preclinical Drug Assessment

$59,418

Mechanisms of Motoneuron Degeneration in Spinal Muscular Atrophy and Identification of Therapeutic Targets

Co-investigatorCIHR2008Emerging Team Grant: From Genes to Proteins, Cells, Tissues and Patients - LOI

Principal investigators: Jasmin, Bernard J; Kothary, Rashmi K

Keywords: Neuromuscular Junction - Mouse Models - Signalling -; Proteomics; Rna Stability - Rna Binding Proteins - Microrna -; Spinal Muscular Atrophy - Motoneurons - Skeletal Muscle -

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Alexander Mackenzie

Research

Latest papers

Latest funding

Development of a riboflavin-responsive model of riboflavin transporter deficiency in zebrafish.

Lactobacillus plantarum 299v Prevents Caspase-Dependent Apoptosis In Vitro.

Pulse probiotic administration induces repeated small intestinal Muc3 expression in rats.

Accelerating drug repurposing for rare neurological, neurometabolic and neuromuscular diseases by exploiting SIMilarities in clinical and molecular PATHology (SIMPATHIC)