Theodore Perkins

OPMDx- Canadian Oculopharyngeal Muscular Dystrophy Biomarkers Study

Principal investigators: Warman Chardon, Jodi

Keywords: Blood Biomarkers; Clinical Assessment; Machine Learning; Muscle Mri; Muscular Dystrophy; Oculopharyngeal Muscular Dystrophy

Regulation of the epigenome by replication stress in vascular disease and aging

Principal investigators: Stanford, William L; Hendzel, Michael J

Keywords: Chromatin Conformation And Architecture; Disease Modeling; Epigenome; Human Induced Pluripotent Stem Cells (Ipscs); Replication Stress; Vascular Aging

Mechanistic insights into non-malignant hematopoietic diseases

Principal investigators: Brand, Marjorie C

Keywords: Arrested Cell Differentiation; Cell Biology; Diamond-Blackfan Anemia; Erythropoiesis; Gene Regulatory Network; Mass Cytometry (Cytof); Quantitative Mass Spectrometry; Quantitative Proteomics; Ribosomopathy; Transcriptomics

Improving detection in high-throughput sequencing data with gene/locus-specific models

Principal investigators: Perkins, Theodore

Metabolomics Advanced Training and International Exchange (CREATE-MATRIX)

Principal investigators: Harper, MaryEllen

Computational quantification of germ layer components in teratomas derived from pluripotent stem cells

Principal investigators: Wang, Dao Sen

Keywords: Ics Studentship

Role of oncogenic transcription factors in T-cell acute lymphoblastic leukemia

Principal investigators: Brand, Marjorie C

Keywords: Chromatin Immunoprecipitation And Sequencing; Epigenetics; Gene Expression Profiling; Knock Down; Oncogenes; Proteomics; Rna Sequencing; T-Cell Acute Lymphoblastic Leukemia; Transcription Factors; Xenograft

The role of PCL2/PRC2 in hematopoietic stem cells and leukemia

Principal investigators: Stanford, William L; Ito, Caryn; Perkins, Theodore J; Sabloff, Mitchell

Keywords: Cell Fate; Chip-Sequencing; Gene Regulatory Networks; Hematopoiesis; Hematopoietic Stem Cells; Leukemia; Polycomb; Transcriptomics; Tumor Suppressor; Xenotransplantation

Inference and Scaling in Stochastic Dynamical Systems

Principal investigators: Perkins, Theodore

Tailored Oncolytic Viral Therapeutics for Pancreatic Cancer

Principal investigators: Bell, John C

Keywords: Cancer Therapy; Molecular Biology; Oncolytic Virus; Pancreatic Cancer; Shrna Library; Tumour Targeting; Viral Evolution; Virus Engineering