Alan Davidson

Canada Research Chair - Tier 1

Principal investigators: Davidson, Alan R

Keywords: Crc

Investigating the battle between CRISPR-Cas systems and anti-CRISPRs using biochemical, genetic, and evolutionary approaches

Principal investigators: Davidson, Alan R

Keywords: Anti-Crispr; Bacteriophage; Biophysical Methods; Crispr-Cas; Evolution; Genetic Selection; In Vitro Assays; Mutagenesis; Protein Design; Virus

Canada Research Chair - Tier 1 - CIHR Funded

Principal investigators: Davidson, Alan R

Keywords: Crc

Studies on a Widely Distributed Phage Tail-Derived Toxin Injection System

Principal investigators: Davidson, Alan

Developing phage tail-derived nanomachines as strain specific antibacterial agents

Principal investigators: Davidson, Alan R

Keywords: Anti-Bacterial Agents; Bacteriology; Bacteriophage; Pathogenic Bacteria; Phage Tails; Structural Biology

High-throughput screen for protein inhibitors of CRISPR-Cas systems: discovery and mechanistic categorization

Principal investigators: Trost, Chantel N

Keywords: Anti-Crispr Proteins; Bacterial Two-Hybrid; Bioinformatics; Crispr-Cas; Genomic Dna Libraries; High-Throughput Functional Screen; Mechanisms Of Inhibition And Modulation; Protein-Protein Interactions; Type I-F

Exploring the evolutionary battle between phages and bacteria: from CRISPR-Cas systems to phage-derived antibacterial weapons

Principal investigators: Davidson, Alan R

Keywords: Anti-Crispr; Bacteriophage; Crispr-Cas; Phage Tail

CRISPR-Cas inhibitors: Investigating their prevalence, diversity, and mechanisms of action

Principal investigators: Pawluk, April

Keywords: Bacteriophage; Crispr-Cas; Genetics; Inhibitors; Molecular Mechanisms; Pseudomonas Aeruginosa; Specificity; Structural Biology

Characterization of Newly Discovered Proteins that Inhibit the CRISPR/Cas Adaptive Immunity Systems of Bacteria

Principal investigators: Davidson, Alan R

Keywords: Bacterial Immunity; Bacteriophage; Crispr/Cas System; Crystallography; Evolution; Nmr Spectroscopy; Prophage; Rna Interference; Site-Directed Mutagenesis

In Vitro, In Vivo, and Bioinformatic Studies on the Function of SH3 Domains

Principal investigators: Davidson, Alan R

Keywords: Bioinformatics; Biophysical Assays; Evolution; Protein-Protein Interaction; Sh3 Domain; Signal Transduction; Site-Directed Mutagenesis; Trp Fluorescence; Yeast