Cordula Enenkel, University of Toronto

Research

Fluorescent Labelling Techniques Neurodegenerative Diseases Nuclear Transport Post-Translational Modifications Proteasome Ubiquitin System Protein Degradation Protein Droplets In Quiescence Quality Control

Latest papers

Metabolically regulated proteasome supramolecular organization in situ.
Cell · 2026 · senior author
Proteasome dynamics in response to metabolic changes.
Frontiers in cell and developmental biology · 2025 · first author
Intracellular localization of the proteasome in response to stress conditions.
The Journal of biological chemistry · 2022 · first author

All 15 publications

Latest funding

Upgrade Advanced EPR/DEER Spectroscopy Facility
NSERC · 2020 · Co-investigator
$150,000
Signaling pathways to protect macromolecular assemblies from degradation
NSERC · 2019 · Principal investigator
$64,000
Dynamic Organization of Proteasomes Droplets in Quiescence in Yeast
CIHR · 2014 · Nominated PI
$717,360

All 4 grants and awards

15 publications.

01

Metabolically regulated proteasome supramolecular organization in situ.

Tang X, Qu L, Wilfling F, Beck F, Ernst OP, Schulman BA, Baumeister W, Enenkel C

Cell2026Senior author

DOI: 10.1016/j.cell.2025.12.035 PMID: 41605212

02

Proteasome dynamics in response to metabolic changes.

Enenkel C, Ernst OP

Frontiers in cell and developmental biology2025First author

DOI: 10.3389/fcell.2025.1523382 PMID: 40099196

03

Intracellular localization of the proteasome in response to stress conditions.

Enenkel C, Kang RW, Wilfling F, Ernst OP

The Journal of biological chemistry2022First author

DOI: 10.1016/j.jbc.2022.102083 PMID: 35636514

04

Editorial: Intracellular Proteasome Dynamics.

Enenkel C, Marshall RS, Vierstra RD

Frontiers in molecular biosciences2020First author

DOI: 10.3389/fmolb.2020.00143 PMID: 32850951

05

Nuclear Transport of Yeast Proteasomes.

Wendler P, Enenkel C

Frontiers in molecular biosciences2019Senior author

DOI: 10.3389/fmolb.2019.00034 PMID: 31157235

06

The paradox of proteasome granules.

Enenkel C

Current genetics2018First author

DOI: 10.1007/s00294-017-0739-y PMID: 28835998

07

Ubiquitin orchestrates proteasome dynamics between proliferation and quiescence in yeast.

Gu ZC, Wu E, Sailer C, Jando J, Styles E, Eisenkolb I, Kuschel M, Bitschar K, Wang X, Huang L, Vissa A, Yip CM, Yedidi RS, Friesen H, Enenkel C

Molecular biology of the cell2017Senior author

DOI: 10.1091/mbc.e17-03-0162 PMID: 28768827

08

Proteasome dynamics between proliferation and quiescence stages of Saccharomyces cerevisiae.

Yedidi RS, Fatehi AK, Enenkel C

Critical reviews in biochemistry and molecular biology2016Senior author

DOI: 10.1080/10409238.2016.1230087 PMID: 27677933

09

Nuclear Import of Yeast Proteasomes.

Burcoglu J, Zhao L, Enenkel C

Cells2015Senior author

DOI: 10.3390/cells4030387 PMID: 26262643

10

Intracellular Dynamics of the Ubiquitin-Proteasome-System.

Chowdhury M, Enenkel C

F1000Research2015Senior author

DOI: 10.12688/f1000research.6835.2 PMID: 26339477

Upgrade Advanced EPR/DEER Spectroscopy Facility

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: Ernst, Oliver

$150,000

Signaling pathways to protect macromolecular assemblies from degradation

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Enenkel, Cordula

$64,000

Dynamic Organization of Proteasomes Droplets in Quiescence in Yeast

Nominated PICIHR2014Operating Grant

Principal investigators: Enenkel, Cordula

Keywords: Fluorescent Labelling Techniques; Neurodegenerative Diseases; Nuclear Transport; Post-Translational Modifications; Proteasome Ubiquitin System; Protein Degradation; Protein Droplets In Quiescence; Quality Control; Yeast Cell Biology; Yeast Genetics

$717,360

Regulation of proteasome homeostasis in yeast

Principal investigatorNSERC2011Discovery Grants Program - Individual

Principal investigators: Enenkel, Cordula

$180,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Applying for

Paper to mentionMention their NSERC grant from 2019

Subject: Prospective PhD student: Fluorescent Labelling Techniques Dear Professor Enenkel, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Metabolically regulated proteasome supramolecular organization in situ." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Signaling pathways to protect macromolecular assemblies from degradation" (2019), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]