Haley Wyatt

Multi-parameter characterization of macromolecular structure and dynamics

Principal investigators: Houry, Walid

Keywords: protein stability; protein oligomerization; protein structure; protein-protein interaction; protein-ligand interaction; nano-differential scanning fluorimetry; dynamic light scattering; static light scattering; back reflection; thermal melt

The SLX4 scaffold protects cells from topoisomerase 2-mediated stress in mitosis

Principal investigators: Aprosoff, Camila

Keywords: Ics Travel Awards

Investigating how chromatin remodeling regulates homologous recombination

Principal investigators: Wyatt, Haley

Keywords: genome stability; homologous recombination; holliday junction resolution; g-quadruplex; chromatin; structure-selective endonuclease; slx4; atrx; biochemistry; molecular biology

6th Canadian Symposium on Telomeres and Genome Integrity

Principal investigators: Wyatt, Haley D

Keywords: Aging; Cancer; Carcinogens; Chromosome Stability; Dna Damage; Dna Repair; Genome Integrity; National Symposium; Telomerase; Telomeres

A unified approach to determine how MUS81-EME1 recognizes and cleaves branched DNA structures to safeguard genome integrity

Principal investigators: Wyatt, Haley D

Keywords: Biochemistry; Cancer; Cellular Senescence; Dna Repair; Genome Stability; Molecular Biology; Mus81-Eme1; Replication Stress; Slx4; Structure-Selective Endonuclease

Automated cryo-plunger for preparation of vitrified samples for cryo-electron microscopy and cryo-electron tomography

Principal investigators: Lee, Jeffrey

Prize 202209PJT - Early Career Award in Cancer: A unified approach to determine how MUS81-EME1 recognizes and cleaves branched DNA structures to safeguard genome integrity

Principal investigators: Wyatt, Haley D

Keywords: Biochemistry; Cancer; Cellular Senescence; Dna Repair; Genome Stability; Molecular Biology; Mus81-Eme1; Replication Stress; Slx4; Structure-Selective Endonuclease

Canada Research Chair - Tier 2

Principal investigators: Wyatt, Haley D

Keywords: Crc

Elucidating the molecular mechanisms of structure-selective endonucleases in DNA repair and genome stability

Principal investigators: Wyatt, Haley

Mechanistic studies of the SMX tri-nuclease with direct links to genome stability

Principal investigators: Wyatt, Haley D

Keywords: Cancer; Complex Structural Variations; Dna Damage & Repair; Dna Endonucleases; Fanconi Anemia; Genetic Disorders; Homologous Recombination; Macromolecular Complexes; Mechanisms Of Genome Instability