Housheng He

Unlocking the Role of RNA Modifications in Prostate Cancer

Principal investigators: He, Housheng H

Keywords: M6a Rna Modification; Prostate Cancer

The N6-methyladenosine Epitranscriptome and Functional Landscape of Lung Adenocarcinoma

Principal investigators: He, Housheng H; Tsao, Ming-Sound

Keywords: M6a Rna Modification

Deciphering the pan-cancer functional landscape of circular RNAs in primary versus acquired resistance to immunotherapy for precision oncology

Principal investigators: Her, Peter

Keywords: Bioinformatics; Biomarker Discovery; Cancer Biology; Circular Rna; Genomics; Immuno-Oncology; Immunotherapy Resistance; Machine Learning; Noncoding Rna; Transcriptomics

Canada Research Chair - Tier 1

Principal investigators: He, Housheng H

Keywords: Crc

Charting the dedifferentiation roadmap of pancreatic neuroendocrine tumours

Principal investigators: Michael, Iacovos P

Keywords: Cancer Cell Plasticity; Dedifferentiation; Hmgb3; Mir-181; Pancreatic Neuroendocrine Tumors

Function of LSD1 in aggressive prostate cancer

Principal investigators: He, Housheng H

Keywords: Epigenetic Regulation; Histone Modification; Lsd1; Prostate Cancer

In vivo CRISPR screen to identify clinically relevant therapeutic targets for lung cancer

Principal investigators: Schramek, Daniel

Keywords: Cancer Research; Crispr/Cas9 Screening; Drug Target Discovery; Functional Genomics; Molecular Biology

Express delivery of RNA therapeutics to cancer

Principal investigators: Zheng, Gang

Discovering druggable targets in advanced prostate cancer with in vivo CRISPR screens

Principal investigators: Xue, Yibo

Keywords: Cancer Biology; Crispr; Druggable Targets; Genetic Screen; Patient Derived Xenografts; Prostate Cancer

Alternatively and trans-spliced isoforms as a new class of biomarkers of response to cytotoxic and targeted therapies in metastatic triple-negative breast cancer

Principal investigators: Haibe-Kains, Benjamin

Keywords: Breast Cancer