James Carlyle, University of Toronto

Research

Innate Immunity Co-Evolution Host-Pathogen Interactions Immunoevasin Mouse Cytomegalovirus Natural Killer Cell Nkr-P1:Clr Self-Nonself Discrimination

Latest funding

Molecular evolution of self-nonself discrimination by paired NKR-P1 receptors, self ligands, and viral immunoevasins
CIHR · 2018 · Nominated PI
$650,250
Molecular mechanisms of natural killer (NK) and innate lymphoid cell (ILC) development and function in health and disease
CIHR · 2015 · Nominated PI
$672,628
NK cell receptor-ligand interactions in recognition of tumour cells and infected targets.
CIHR · 2010 · Nominated PI
$677,345

All 4 grants and awards

Molecular evolution of self-nonself discrimination by paired NKR-P1 receptors, self ligands, and viral immunoevasins

Nominated PICIHR2018Project Grant

Principal investigators: Carlyle, James R

Keywords: Co-Evolution; Host-Pathogen Interactions; Immunoevasin; Innate Immunity; Mouse Cytomegalovirus; Natural Killer Cell; Nkr-P1:Clr; Self-Nonself Discrimination; Viral Immune Evasion; X-Ray Crystal Structure

$650,250

Molecular mechanisms of natural killer (NK) and innate lymphoid cell (ILC) development and function in health and disease

Nominated PICIHR2015Operating Grant

Principal investigators: Carlyle, James R

Keywords: Cancer; Colitis; Cytomegalovirus; Development; Gene Regulation; Immune Evasion; Infection; Innate Immunity; Innate Lymphoid Cells (Ilc); Natural Killer (Nk) Cells

$672,628

NK cell receptor-ligand interactions in recognition of tumour cells and infected targets.

Nominated PICIHR2010Operating Grant

Principal investigators: Carlyle, James R

Keywords: Cancer; Cytomegalovirus; Gene Regulation; Infection; Innate Immunity; Natural Killer Cells

$677,345

The role of NKR-P1B:Clr-b missing-self axis in NK cell-mediated innate immunity to infection

SupervisorCIHR2008Doctoral: Vanier Canada Graduate Scholarships

Principal investigators: Mesci, Aruz

Keywords: Cytomegalovirus; Immune Evasion; Infectious Disease; Innate Immunity; Molecular Cloning; Monoclonal Antibodies; Nk Cells; Reporter Cell Assays; Virology

$150,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Applying for

Subject: Prospective PhD student: Innate Immunity Dear Professor Carlyle, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. Your research on innate immunity connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]