Faculty profile

John Brumell

ResearcherCell BiologyUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

John Brumell

Researcher

Cell Biology

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
No publications since 2009.
Principal investigator on 18 research grants (15 CIHR, 3 NSERC), most recently in 2024.
Supervised 9 trainees who won CIHR awards, most recently in 2015.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Inflammatory Bowel Disease Inflammation Listeria Monocytogenes Autophagy Cell Death Cell-To-Cell Spread Inflammatory Bowel Diseases Innate Immunity

Latest papers

Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic beta-cells.
American journal of physiology. Endocrinology and metabolism · 2009

All 1 publications

Latest funding

Mechanisms that regulate plasma membrane dynamics during Salmonella invasion
CIHR · 2024 · Nominated PI
$1,021,276
Characterizing deep invaginations of the plasma membrane
NSERC · 2024 · Principal investigator
$55,000
Mechanisms of long-distance spread in host tissues by Listeria monocytogenes
CIHR · 2023 · Nominated PI
$100,000

All 31 grants and awards

Mechanisms that regulate plasma membrane dynamics during Salmonella invasion

Nominated PICIHR2024Project Grant

Principal investigators: Brumell, John H

Keywords: Bacterial Invasion; Gastroenteritis; Inflammatory Bowel Disease; Lrrk2; Membrane Reservoirs; Parkinson'S Disease; Plasma Membrane; Rab10; Salmonella; Tlr4

$1,021,276

Characterizing deep invaginations of the plasma membrane

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Brumell, John

Keywords: plasma membrane; gtpase signaling; rab10; membrane tubulation; endocytosis; phagocytosis; signal transduction; membrane damage; membrane repair; host-pathogen interactions

$55,000

Mechanisms of long-distance spread in host tissues by Listeria monocytogenes

Nominated PICIHR2023Project Grant

Principal investigators: Brumell, John H

Keywords: Cell Death; Cell Motility; Cell-To-Cell Spread; Cyld; Ikk; Inflammation; Internalin C; Listeria Monocytogenes; Nf-Kb; Systemic Infection

$100,000

Mechanisms of long-distance spread in host tissues by Listeria monocytogenes

Nominated PICIHR2023Project Grant

Principal investigators: Brumell, John H

Keywords: Cell Death; Cell Motility; Cell-To-Cell Spread; Cyld; Ikk; Inflammation; Internalin C; Listeria Monocytogenes; Nf-Kb; Systemic Infection

$1,032,750

Hurdling the liver to improve gene therapy

Co-investigatorSSHRC2020New Frontiers in Research Fund - Exploration

Principal investigators: Dowling, James

$250,000

Defining the immune dysregulation underlying Pediatric IBD to better diagnose and treat patients.

Principal investigatorCIHR2019Autoimmune diseases related to digestive system, kidney, pancreas and liver pool

Principal investigators: Muise, Aleixo M; Brumell, John H; Gruenheid, Samantha L; Mortha, Arthur; Vallance, Bruce A

Keywords: Lysosome-Mediated Cellular Repair; Oraganoids; Pediatrics; Sex And Gender; Ulcerative Colitis

$1,514,500

Defining the immuno-dysregulation underlying Pediatric IBD to better diagnose and treat patients.

Principal investigatorCIHR2018Team Grant: Human Immunology Initiative: Research Teams - LOI

Principal investigators: Muise, Aleixo M; Brumell, John H; Gruenheid, Samantha L; Mortha, Arthur; Vallance, Bruce A

Keywords: Children; Drug Treatment; Enteroids; Immune Dysregulation; Inflammatory Bowel Disease; Mouse Models; Pediatrics

$20,000

Developing Targeted Therapies for Rare and Common Forms of Inflammatory Bowel Disease

Co-investigatorCIHR2018Foundation Grant

Principal investigators: Muise, Aleixo M

Keywords: Drug Screening; Genetics; Inflammatory Bowel Disease; Monogenic Defects; Pediatrics; Zebrafish

$2,955,578

Proteomic studies of autophagy and its defects in Inflammatory Bowel Disease

Nominated PICIHR2016Project Grant

Principal investigators: Brumell, John H; Kim, Peter K; Raught, Brian

Keywords: Autophagy; Crohn'S Disease; Gastrointestinal Diseases; Inflammation; Inflammatory Bowel Disease; Innate Immunity; Lysosome; Proteomics; Signal Transduction; Ulcerative Colitis

$642,180

Innate immunity and its disruption by microbial and genetic factors

Nominated PICIHR2016Foundation Grant

Principal investigators: Brumell, John H

Keywords: Autophagy; Bacterial Infections; Inflammatory Bowel Diseases; Innate Immunity; Listeria Monocytogenes; Nadph Oxidases; Phagocytosis; Proteomics; Reactive Oxygen Species; Salmonella Typhimurium

$4,492,432

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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John Brumell

Research

Latest papers

Latest funding

Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic beta-cells.

Characterizing deep invaginations of the plasma membrane

Hurdling the liver to improve gene therapy