Juan Zuniga-Pflucker

Progenitor T cells for immune-regeneration (ProTregen)

Principal investigators: Zuniga-Pflucker, Juan Carlos

Keywords: Cell-Based Immunotherapy; Hematopoietic Stem Cell Transplant; Notch Signaling; Progenitor T Cells

Progenitor T-cells as key mediators to re-establish T-cell immunity

Principal investigators: Zuniga-Pflucker, Juan Carlos

Keywords: Aging Of The Immune System; Cell-Based Therapy; Hematopoietic Stem Cell Transplant; Lymphocyte Progenitors; Notch Signaling; T Cell Regeneration

Regulation of Delta-like 4 in Thymic Epithelial Cells as a Model for Organ Structure Affecting Gene Regulation

Principal investigators: Zuniga-Pflucker, Juan Carlos

Keywords: thymus; developmental immunology; notch signaling; gene regulation; thymus epithelial cells; foxn1; dll4

Notch signaling in the generation of mature naïve conventional and regulatory T cells

Principal investigators: Zuniga-Pflucker, Juan Carlos

Keywords: Notch Signaling; T Cell Differentiation

Data-driven Cell Fate Engineering to produce biomedically compatible off-the-shelf T cell therapeutics

Principal investigators: Rajan, Vinothkumar

Keywords: Hematopoietic Stem Cell Differentiation; Immunotherapy; Lineage Tracing; Single-Cell Sequencing; T-Cell Differentiation

Understanding how the immune system is important in heart failure

Principal investigators: Sung, Hyekyoung

Keywords: Adiponectin; Heart Failure; Innate Immunity; Macrophage; Neutrophil; Sterile Inflammation; T-Cells

Efficacy of Viral RNA Processing Inhibitors in Controlling HIV-1 Replication in vivo

Principal investigators: Wong, Raymond

Keywords: Antiviral; Chemical Biology; Drugs; Flow Cytometry; High Throughput Screens; Hiv/Aids; In Vivo Validation; Mice; Rna; Stem Cells

The Regulation of Delta-like 4 in Thymic Epithelial Cells as a Model for Organ Structure Affecting Gene Regulation

Principal investigators: ZunigaPflucker, JuanCarlos

Engineering stem cell fate and function

Principal investigators: Zandstra, Peter W

Keywords: Blood Development; Cell Reprogramming; Computational Modeling; Hematopoietic Stem Cells; Mesoderm; Microenvironmental Control; Niche Engineering; Pluripotent Stem Cells; Stem Cells

Cellular and molecular characterization of T cell development for immune-reconstitution

Principal investigators: Zuniga-Pflucker, Juan Carlos

Keywords: Gamma-Delta T Cells; Hematopoietic Stem Cells; Immune Reconstitution; Notch Signaling; T Cell Development; Thymus