Long Nguyen, University of Toronto

Research

Cancer Stem Cell Biology Clonal Heterogeneity Human Breast Cancer Single Cell Sequencing Human Triple-Negative Breast Cancer Phenotypic Plasticity

Latest papers

The tumor microenvironment of 14,837 breast cancers is associated with clinical outcome independently of genomic subtypes.
Cell reports. Medicine · 2025
Inhibition of Rab prenylation by statins induces cellular glycosphingolipid remodeling.
Glycobiology · 2016

All 2 publications

Latest funding

Functional properties and genetic dependencies of phenotypic plasticity in human triple-negative breast cancer
CIHR · 2025 · Nominated PI
$25,000
Functional properties and genetic dependencies of phenotypic plasticity in human triple-negative breast cancer
CIHR · 2025 · Nominated PI
$1,147,500
Mapping early ecosystem reprogramming in high-risk breast tissue for cancer prevention
CIHR · 2025 · Co-investigator
$1,067,175

All 5 grants and awards

2 publications.

01

The tumor microenvironment of 14,837 breast cancers is associated with clinical outcome independently of genomic subtypes.

Tu KJ, Guerrero-Romero D, Eason K, Manzano Garcia R, Wern J, Teo SH, Nguyen L, Sammut SJ, Markowetz F, Rueda OM, Caldas C

Cell reports. Medicine2025

DOI: 10.1016/j.xcrm.2025.102450 PMID: 41218603

02

Inhibition of Rab prenylation by statins induces cellular glycosphingolipid remodeling.

Binnington B, Nguyen L, Kamani M, Hossain D, Marks DL, Budani M, Lingwood CA

Glycobiology2016

DOI: 10.1093/glycob/cwv084 PMID: 26405105

Functional properties and genetic dependencies of phenotypic plasticity in human triple-negative breast cancer

Nominated PICIHR2025PRIZE - Project Grant - PA: Prize: Early Career Investigator in Cancer

Principal investigators: Nguyen, Long V

Keywords: Human Triple-Negative Breast Cancer; Phenotypic Plasticity

$25,000

Functional properties and genetic dependencies of phenotypic plasticity in human triple-negative breast cancer

Nominated PICIHR2025Project Grant

Principal investigators: Nguyen, Long V

Keywords: Cancer Stem Cell Biology; Clonal Heterogeneity; Human Breast Cancer; Single Cell Sequencing

$1,147,500

Mapping early ecosystem reprogramming in high-risk breast tissue for cancer prevention

Co-investigatorCIHR2025Project Grant

Principal investigators: Gaiti, Federico

Keywords: Breast Cancer; Cancer Prevention; Epithelial-Stromal Interactions; Fibroblasts; High-Risk Mutation Carriers; Hormonal Regulation; Organoid Models; Single-Cell Omics; Spatial Omics; Tumor Microenvironment

$1,067,175

TET2-mutant clonal hematopoiesis as a determinant of breast cancer survival

Co-investigatorCIHR2025Project Grant

Principal investigators: Vanner, Robert J

Keywords: Breast Cancer; Cancer; Clonal Hematopoiesis; Genomics; Immunology; Metastasis

$1,086,300

Sentinel lympH node biopsy with Indocyanine green in breast cancer after NEoadjuvant therapy (SHINE)

Co-investigatorCIHR2024Project Grant

Principal investigators: Kazazian, Karineh

Keywords: Axillary Staging; Breast Cancer; Equity; Indocyanine Green; Patient Reported Outcomes; Sentinel Lymph Node Biopsy; Surgical Quality

$279,224

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Cancer Stem Cell Biology Dear Professor Nguyen, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "The tumor microenvironment of 14,837 breast cancers is associated with clinical outcome independently of genomic subtypes." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Functional properties and genetic dependencies of phenotypic plasticity in human triple-negative breast cancer" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]