Maria Nostro, University of Toronto

Research

Beta Cells Regenerative Medicine Diabetes Pancreas Development Directed Differentiation Human Pluripotent Stem Cells Transplantation Entero Endocrine Cells

Latest funding

Engineering GLP-1-secreting cells from human pluripotent stem cells to enhance beta cell replacement therapies
CIHR · 2025 · Nominated PI
$952,425
Determining the therapeutic potential of HLA-deficient human pluripotent stem cell-derived beta-like cells
CIHR · 2020 · Supervisor
$105,000
Using novel transplantation strategies and HLA-edited hypoimmunogenic hPSCs to develop a superior islet-like product for T1D treatment
CIHR · 2020 · Nominated PI
$1,500,000

All 4 grants and awards

Engineering GLP-1-secreting cells from human pluripotent stem cells to enhance beta cell replacement therapies

Nominated PICIHR2025Project Grant

Principal investigators: Nostro, Maria Cristina

Keywords: Beta Cells; Diabetes; Directed Differentiation; Entero Endocrine Cells; Human Pluripotent Stem Cells; Pancreas Development; Pancreatic Endocrin Cells; Regenerative Medicine; Transplantation

$952,425

Determining the therapeutic potential of HLA-deficient human pluripotent stem cell-derived beta-like cells

SupervisorCIHR2020Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Misra, Paraish S

Keywords: Allorejection; Cell Therapy; Diabetes Mellitus; Human Pluripotent Stem Cells; Transplantation

$105,000

Using novel transplantation strategies and HLA-edited hypoimmunogenic hPSCs to develop a superior islet-like product for T1D treatment

Nominated PICIHR2020Team Grant: CIHR-JDRF-Accelerating Stem Cell-Based Therapies for Type 1 Diabetes

Principal investigators: Nostro, Maria Cristina; Drucker, Daniel J; Korbutt, Gregory S; Pepper, Andrew R; Vasconcelos, Sara N

Keywords: Beta Cells; Directed Differentiation; Hla-Editing; Human Pluripotent Stem Cells; Humanized Mice; Regenerative Medicine; Transplantation; Type 1 Diabetes

$1,500,000

Developing functional beta cells for diabetes treatment

Nominated PICIHR2018Project Grant

Principal investigators: Nostro, Maria Cristina

Keywords: Beta Cell Function; Beta Cells; Cell Sorting; Diabetes; Human Embryonic Stem Cells; Human Induced Pluripotent Stem Cells; Pancreas Development; Regenerative Medicine; Transcriptome; Transplant

$879,750

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

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Applying for

Mention their CIHR grant from 2025

Subject: Prospective PhD student: Beta Cells Dear Professor Nostro, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. Your research on beta cells connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Engineering GLP-1-secreting cells from human pluripotent stem cells to enhance beta cell replacement therapies" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]