Michael Norris, University of Toronto

Research

Cryo-Electron Microscopy (Cryo-Em)Cryo-Electron Tomography (Cryo-Et Mass Photometry Matrix Protein Membrane Lipids Paramyxovirus Protein Oligomerization Scanning Electron Microscopy (Sem)

Latest papers

Anti-Ebola virus mAb 3A6 with unprecedented potency protects highly viremic animals from fatal outcome and physically lifts its glycoprotein target from the virion membrane.
Research square · 2023

All 1 publications

Latest funding

Multi-parameter characterization of macromolecular structure and dynamics
NSERC · 2025 · Co-investigator
$150,000
Strengthening a One Health approach for highly pathogenic avian influenza viruses; Advancing a biological trajectory for viral risk assessment
CIHR · 2024 · Co-investigator
Dynamic plasticity of paramyxovirus matrix proteins
NSERC · 2023 · Principal investigator
$12,500

All 6 grants and awards

1 publications.

01

Anti-Ebola virus mAb 3A6 with unprecedented potency protects highly viremic animals from fatal outcome and physically lifts its glycoprotein target from the virion membrane.

Saphire E, Salie ZL, Ke Z, Halfmann P, DeWald LE, McArdle S, Grinyo A, Davidson E, Schendel S, Hariharan C, Norris M, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook M, Doranz B, Crozier I, Hastie K, Kawaoka Y, Branco L, Kuhn J, Briggs J, Worwa G, Davis C, Ahmed R

Research square2023

DOI: 10.21203/rs.3.rs-3722563/v1 PMID: 38196595

Multi-parameter characterization of macromolecular structure and dynamics

Co-investigatorNSERC2025Research Tools and Instruments

Principal investigators: Houry, Walid

Keywords: protein stability; protein oligomerization; protein structure; protein-protein interaction; protein-ligand interaction; nano-differential scanning fluorimetry; dynamic light scattering; static light scattering; back reflection; thermal melt

$150,000

Strengthening a One Health approach for highly pathogenic avian influenza viruses; Advancing a biological trajectory for viral risk assessment

Co-investigatorCIHR2024Catalyst Grant: Avian Influenza OneHealth Research

Principal investigators: Mubareka, Samira

Keywords: Domestic Animals; Highly Pathogenic Avian Influenza Virus; Humans; Organoids; Primary Epithelial Cells; Replication; Risk Assessment; Wildlife

Dynamic plasticity of paramyxovirus matrix proteins

Principal investigatorNSERC2023Discovery Launch Supplement

Principal investigators: Norris, Michael

$12,500

Dynamic plasticity of paramyxovirus matrix proteins

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Norris, Michael

Keywords: Electron Cryomicroscopy (Cryo-EM); Matrix protein; Multifunctional Proteins; Paramyxovirus; Protein Oligomerization; Structural Biology; Virology; Virus Assembly

$66,000

Exploring the molecular architecture of the human multisynthetase complex

Co-investigatorCIHR2023Project Grant

Principal investigators: Cui, Haissi

Keywords: Aminoacyl-Trna Synthetase; Cancer Cell Signaling; Cellular Signaling; Cryo-Em; Genetic Code; Metabolism; Mrna Translation; Neurodevelopmental Disorder; Nucleic Acids; Trnas

$956,250

Investigating the Mechanisms of Paramyxovirus Assembly: Implications for Antiviral Therapeutic Design

Nominated PICIHR2023Project Grant

Principal investigators: Norris, Michael

Keywords: Cryo-Electron Microscopy (Cryo-Em); Cryo-Electron Tomography (Cryo-Et; Mass Photometry; Matrix Protein; Membrane Lipids; Paramyxovirus; Protein Oligomerization; Scanning Electron Microscopy (Sem); Super-Resolution Microscopy; Virus Assembly

$1,049,485

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

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Applying for

Mention their NSERC grant from 2023

Subject: Prospective PhD student: Cryo-Electron Microscopy (Cryo-Em) Dear Professor Norris, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Anti-Ebola virus mAb 3A6 with unprecedented potency protects highly viremic animals from fatal outcome and physically lifts its glycoprotein target from the virion membrane." (2023), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Dynamic plasticity of paramyxovirus matrix proteins" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]