Faculty profile
Michelle Bendeck
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Research
Latest papers
SMC-Derived Hyaluronan Modulates Vascular SMC Phenotype in Murine Atherosclerosis.
Circulation research · 2021
Role of smooth muscle cells in coronary artery bypass grafting failure.
Cardiovascular research · 2018
In Memoriam: B. Lowell Langille (1947-2008).
Circulation research · 2009 · first author
Latest funding
- $975,376
Peptide-Nanoparticle Drug Delivery System
CIHR · 2026 · Nominated PI
- $120,000
Targeting Pediatric Vascular Stenoses using Pediatric HiPSC-derived Smooth Muscle Cells with N-Cadherin Mimetic Peptide Nanoparticle Drug Delivery
CIHR · 2025 · Supervisor
- $967,725
Molecular Mechanisms of Arterial Stiffening in Calcification
CIHR · 2025 · Nominated PI
4 publications.
SMC-Derived Hyaluronan Modulates Vascular SMC Phenotype in Murine Atherosclerosis.
Hartmann F, Gorski DJ, Newman AAC, Homann S, Petz A, Owsiany KM, Serbulea V, Zhou YQ, Deaton RA, Bendeck M, Owens GK, Fischer JW
Role of smooth muscle cells in coronary artery bypass grafting failure.
Wadey K, Lopes J, Bendeck M, George S
In Memoriam: B. Lowell Langille (1947-2008).
Bendeck M, Gotlieb A
Migration and growth are attenuated in vascular smooth muscle cells with type VIII collagen-null alleles.
Adiguzel E, Hou G, Mulholland D, Hopfer U, Fukai N, Olsen B, Bendeck M
Peptide-Nanoparticle Drug Delivery System
Principal investigators: Bendeck, Michelle P
Keywords: Angioplasty Device; Biomaterial; Drug Delivery; Nanoparticles; Peptide; Smooth Muscle Cell
Targeting Pediatric Vascular Stenoses using Pediatric HiPSC-derived Smooth Muscle Cells with N-Cadherin Mimetic Peptide Nanoparticle Drug Delivery
Principal investigators: Adil, Aisha
Keywords: Cardiovascular Matrix Biology; Congenital Heart Disease; Extracellular Matrices; Heart Failure; Human Induced Pluripotent Stem Cells; N-Cadherin; Nanoparticle Drug Delivery; Pediatric Stem Cell Application; Pediatric Vascular Stenoses; Smooth Muscle Cells
Molecular Mechanisms of Arterial Stiffening in Calcification
Principal investigators: Bendeck, Michelle P
Keywords: Atherosclerosis; Discoidin Domain Receptor; Extracellular Matrix; Human Tissue; Intracellular Signalng; Mechanotransduction; Smooth Muscle Cell; Transgenic Mice; Vascular Calcification
A Peptide-Nanoparticle Delivery System for the Vasculature
Principal investigators: Bendeck, Michelle
Peptide-Conjugated Nanoparticles to Inhibit Cell Migration in Restenosis
Principal investigators: Bendeck, Michelle
Mechanisms of Arterial Stiffening in Calcification
Principal investigators: Bendeck, Michelle P
Keywords: Atherosclerosis; Calcification; Discoidin Domain Receptor; Extracellular Matrix; Human Tissue; Mechanotransduction; Mouse Models Of Disease; Smooth Muscle Cells; Transgenic Mice; Vascular Stiffening
Enabling the Engineering of Vascular Grafts with Human Cells-Appliations to Pulmonary Arterial Grafting
Principal investigators: Santerre, Paul
Keywords: Adipose Stem Cells; Biomaterials; Biomechanics; Blood; Endothelial Cells; Monocytes; Tissue Engineering; Vascular Graft; Vascular Pathology; Vascular Smooth Muscle Cells
Multi-colour super-resolution microscopy for mechanotransduction studies at the single molecule level
Principal investigators: FernandezGonzalez, Rodrigo
Bioreactors for biomechanical conditioning and evaluation of native and engineered tissues
Principal investigators: Simmons, Craig
The Discoidin Domain Receptor-1 Acts as a Mechanotransducer to Promote Vascular Calcification
Principal investigators: Ngai, David
Keywords: Atherosclerosis; Cell Contractility; Cytoskeletal Dynamics; Discoidin Domain Receptor-1; Mechanotransduction; Nuclear Envelope Dynamics; Smooth Muscle Cell; Stiffness; Transdifferentiation; Vascular Calcification
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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