Patricia Brubaker

Establishing the relationship between the intestinotrophic factor glucagon like peptide-2 and the microbiome in neonatal piglets with short bowel syndrome

Principal investigators: Turner, Justine M

Keywords: Glucagon Like Peptide 2; Intestinal Adaptation; Intestinal Failure; Microbiome; Probiotics; Short Bowel Syndrome; Short Chain Fatty Acids

Revolutionizing the treatment of neonatal short bowel syndrome by novel therapeutic approaches to intestinal growth

Principal investigators: Turner, Justine M

Keywords: Epidermal Growth Factor; Glucagon Like Peptide 2; Insulin Like Growth Factor 1; Intestinal Adaptation; Intestinal Failure; Neonate; Parenteral Nutrition; Piglet; Short Bowel Syndrome; Trophic Factors

Mechanisms underlying circadian secretion of the anti-diabetic hormone, glucagon-like peptide-1: therapeutic potential

Principal investigators: Brubaker, Patricia L

Keywords: Cell Signaling; Circadian; Glp-1; Glucose; In Vitro; In Vivo; Insulin; Intestine; Metabolism; Secretion

Elucidating the role of Bmal1 in regulating circadian secretion of glucagon-like peptide-1 from the intestinal L cell

Principal investigators: Martchenko, Alexandre

Keywords: Circadian Rhythms; Diabetes And Metabolic Syndrome; Glucagon-Like Peptide-1; Rhythmic Secretion

Mechanisms dictating the actions of glucagon-like peptide-2, a unique therapeutic for intestinal disorders

Principal investigators: Brubaker, Patricia L

Keywords: Cellular; Glp-2; Growth; Hormone; Intestine; Mechanistic; Molecular; Proliferation; Stem Cells; Whole-Animal

Canada Research Chair Tier 1

Principal investigators: Brubaker, Patricia L

Keywords: Crc

Role of TNF alpha in inflammation-induced impairments in glucagon-like peptide-1 release

Principal investigators: Gagnon, Jeffrey

Keywords: Diabetes; Glucagon-Like Peptide 1; Inflammation

""Role of the SNARE proteins in exocytosis of the intestinal hormone, glucagon-like peptide-1""

Principal investigators: Brubaker, Patricia

Interactions between glucagon-like peptide-2 and intestinal insulin-like growth factor-1 signalling in the regulation of intestinal growth and function

Principal investigators: Brubaker, Patricia L

Keywords: Erbb; Glucagon-Like Peptide-2; Growth; Insulin-Like Growth Factor Receptor; Insulin-Like Growth Factor-1; Intestinal Barrier Function; Intestinal Stem Cells; Intestine; Signaling

Role of fatty acid transport proteins in the stimulatory effects of fatty acids on the secretion of the insulinotropic hormone glucagon-like peptide-1.

Principal investigators: Poreba, Monika

Keywords: Cell Culture; Diabetes; Glucagon-Like Peptide-1 Secretion; In Vitro; In Vivo; Murine; Oleic Acid; Physiology; Radioimmunoassay; Sirna