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Research
Latest papers
Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase.
Autophagy · 2011
Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization.
Molecular and cellular biology · 2008
Latest funding
- $1,514,500
Defining the immune dysregulation underlying Pediatric IBD to better diagnose and treat patients.
CIHR · 2019 · Principal investigator
- $20,000
Defining the immuno-dysregulation underlying Pediatric IBD to better diagnose and treat patients.
CIHR · 2018 · Principal investigator
2 publications.
Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase.
Huang J, Birmingham CL, Shahnazari S, Shiu J, Zheng YT, Smith AC, Campellone KG, Heo WD, Gruenheid S, Meyer T, Welch MD, Ktistakis NT, Kim PK, Klionsky DJ, Brumell JH
Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization.
Blasutig IM, New LA, Thanabalasuriar A, Dayarathna TK, Goudreault M, Quaggin SE, Li SS, Gruenheid S, Jones N, Pawson T
Defining the immune dysregulation underlying Pediatric IBD to better diagnose and treat patients.
Principal investigators: Muise, Aleixo M; Brumell, John H; Gruenheid, Samantha L; Mortha, Arthur; Vallance, Bruce A
Keywords: Lysosome-Mediated Cellular Repair; Oraganoids; Pediatrics; Sex And Gender; Ulcerative Colitis
Defining the immuno-dysregulation underlying Pediatric IBD to better diagnose and treat patients.
Principal investigators: Muise, Aleixo M; Brumell, John H; Gruenheid, Samantha L; Mortha, Arthur; Vallance, Bruce A
Keywords: Children; Drug Treatment; Enteroids; Immune Dysregulation; Inflammatory Bowel Disease; Mouse Models; Pediatrics
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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