Faculty profile

Sean Ong

ResearcherInfectious Diseases/Internal MedicineUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC). We have not imported them from a University of Toronto directory, so their publications, courses and email address may be missing. Find their university profile.

Signals and details

Research

Adaptive Platform Trial Antibiotic De-Escalation Antibiotic Duration Antibiotic Oral Switch Antimicrobial Resistance Bloodstream Infection Central Venous Catheter Infection Gram Negative Bacteremia

Latest funding

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections
CIHR · 2025 · Principal investigator
$1,908,674
An international platform for finding the optimal therapies for Pneumocystis jirovecii pneumonia: The PCP Platform
CIHR · 2024 · Co-investigator
$1,683,000
BALANCE+ PRO (Patient-informed Relevant Outcomes)
CIHR · 2024 · Co-investigator
$309,825

All 8 grants and awards

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Principal investigatorCIHR2025Project Grant

Principal investigators: Daneman, Nick; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Ong, Sean W; Pinto, Ruxandra; Rogers, Benjamin A

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Duration; Antibiotic Oral Switch; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Clinical Trial

$1,908,674

An international platform for finding the optimal therapies for Pneumocystis jirovecii pneumonia: The PCP Platform

Co-investigatorCIHR2024Project Grant

Principal investigators: Lee, Todd C; Benedetti, Andrea; Bhagani, Sanjay; Boyles, Tom; Butler-Laporte, Guillaume; Cheng, Matthew P; McDonald, Emily G; McGuinty, Michaeline; Nakashima, Kei; Schwartz, Ilan S; Slavin, Monica; So, Miranda; Tan, Darrell H; Yong, Michelle

Keywords: Immunomodulation; Platform Trial; Pneumocystis; Pneumonia; Randomized Controlled Trial; Secondary Prophylaxis; Treatment

$1,683,000

BALANCE+ PRO (Patient-informed Relevant Outcomes)

Co-investigatorCIHR2024Project Grant

Principal investigators: Somayaji, Ranjani; Fiest, Kirsten M; Fowler, Robert A

Keywords: Balance+ Trial; Blood Stream Infections; Critical Illness; Health Outcomes; International Study; Mixed-Methods Study; Patient Informed Outcomes; Patients And Family Members; Quality Of Life; Severe Infections

$309,825

Evaluating the impact of a SIMPlified LaYered consent process versus a conventional informed consent form on recruitment of potential participants to a large platform clinical trial: a pragmatic nested randomized controlled trial (SIMPLY-SNAP Trial) - Full Proposal

Principal investigatorCIHR2023Project Grant

Principal investigators: Daneman, Nick; Cheng, Matthew P; Johnstone, Jennie; Lee, Todd C; McDonald, Emily G; Ong, Sean W; Tong, Steven

Keywords: Informed Consent; Patient Education; Process Measures; Randomized Clinical Trials

$149,176

Dexamethasone For Preventing Deterioration In Community Acquired Pneumonia (DEFEND-CAP)

Co-investigatorCIHR2023Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: Zarychanski, Ryan; Lawler, Patrick R; Lother, Sylvain; McDonald, Emily G

Keywords: Bayesian Adaptive Trial; Community Acquired Pneumonia (Cap); Corticosteroids; Dexamethasone; Phase Iii Trial; Randomized Trial

$1,375,000

Dexamethasone For Preventing Deterioration In Community Acquired Pneumonia (DEFEND-CAP)

Co-investigatorCIHR2023Operating Grant: Clinical Trials Projects

Principal investigators: Zarychanski, Ryan; Lawler, Patrick R; Lother, Sylvain; McDonald, Emily G

Keywords: Bayesian Adaptive Trial; Community Acquired Pneumonia (Cap); Corticosteroids; Dexamethasone; Phase Iii Trial; Randomized Trial

$5,500,001

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: Daneman, Nick; Murthy, Srinivas; Yamamura, Deborah L; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Paterson, David L; Rogers, Benjamin A; Yahav, Dafna

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Step-Down; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Controlled Trial

$729,947

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects

$2,919,785

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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