Faculty profile
Stephen Girardin
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Research
Latest papers
Modeling-Enabled Characterization of Novel NLRX1 Ligands.
PloS one · 2015
Nod proteins link bacterial sensing and autophagy.
Autophagy · 2010
Latest funding
- $125,000
In situ monitoring of intestinal mucus barrier regulation in colorectal cancer
SSHRC · 2024 · Principal investigator
- $1,028,925
Induction of intestinal revSCs by a bacterial metabolite
CIHR · 2023 · Nominated PI
- $100,000
Mitochondrial protein import stress (MPIS) pathways
CIHR · 2022 · Nominated PI
2 publications.
Modeling-Enabled Characterization of Novel NLRX1 Ligands.
Lu P, Hontecillas R, Abedi V, Kale S, Leber A, Heltzel C, Langowski M, Godfrey V, Philipson C, Tubau-Juni N, Carbo A, Girardin S, Uren A, Bassaganya-Riera J
Nod proteins link bacterial sensing and autophagy.
Travassos LH, Carneiro LA, Girardin S, Philpott DJ
In situ monitoring of intestinal mucus barrier regulation in colorectal cancer
Principal investigators: Girardin, Stephen
Induction of intestinal revSCs by a bacterial metabolite
Principal investigators: Girardin, Stephen E
Keywords: Adp-Heptose; Crohn'S Disease; Intestinal Organoids; Intestinal Stem Cells; Paneth Cells
Mitochondrial protein import stress (MPIS) pathways
Principal investigators: Girardin, Stephen E
Keywords: Mitochondria; Mitochondrial Stress; Mitophagy; Parkinson'S Disease; Protein Aggregation
A novel role for IL-18 in the control of the intestinal epithelium during infection and inflammation.
Principal investigators: Philpott, Dana J
Keywords: Colorectal Cancer; Crohn'S Disease; Intestinal Infection; Intestinal Inflammation
Canada Research Chairs - Tier 1
Principal investigators: Girardin, Stephen E
Keywords: Crc
Intestinal stem cell regulation by the bacterial metabolite ADP-heptose
Principal investigators: Goyal, Shawn
Keywords: Adp-Heptose; Alpka Kinase 1; Inflammation; Inflammatory Bowel Disease; Intestinal Stem Cells; Microbiota; Single-Cell Rna Seq; Tifa
The impact of early-life enteric infection on the development of Crohn's disease
Principal investigators: Girardin, Stephen E
Keywords: Crohn'S Disease; Enteric Infection; Intestinal Barrier Defense; Nod2
The role of TFEB in innate immune responses to a bacterial pathogen
Principal investigators: Girardin, Stephen
Keywords: Innate immunity; Intracellular bacteria; lysosomes; Shigella; TFEB; Transcription factor
Activation of a cytosolic unfolded protein response to clear aggregating alpha-synuclein
Principal investigators: Girardin, Stephen E
Keywords: Alpha-Synuclein; Parkinson'S Disease; Protein Aggregation; Unfolded Protein Response
CAN-Microbe - The Canadian Microbiome Network
Principal investigators: Guttman, David S; Philpott, Dana J
Keywords: Biobanks; Bioethics; Bioinformatics & Data Analysis; Education & Training; Experimental Consultation; Microbial Cultures; Microbiome Research; Mouse Models; Outreach; Standard Operating Procedures
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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