Thomas Koch, University of Toronto

Research

Antisense Oligonucleotide Cartilage Degeneration Disease Attenuation Efficacy Equine Models Fetlock Joint Micro-Rna Osteoarthritis

Latest funding

Determining the safety and efficacy of microRNA-181a-5p blocker as a potential therapy for the treatment of osteoarthritis
CIHR · 2025 · Principal investigator
$684,675
An intervertebral disc replacement: a regenerative medicine approach
CIHR · 2022 · Co-investigator
$1,170,450

All 2 grants and awards

Determining the safety and efficacy of microRNA-181a-5p blocker as a potential therapy for the treatment of osteoarthritis

Principal investigatorCIHR2025Project Grant

Principal investigators: Kapoor, Mohit; Koch, Thomas G; Koenig, Judith; Rampersaud, Y. Raja

Keywords: Antisense Oligonucleotide; Cartilage Degeneration; Disease Attenuation; Efficacy; Equine Models; Fetlock Joint; Micro-Rna; Osteoarthritis; Safety; Synovitis

$684,675

An intervertebral disc replacement: a regenerative medicine approach

Co-investigatorCIHR2022Project Grant

Principal investigators: Kandel, Rita A

Keywords: Bone Substitute; Crispr/Cas9; Intervertebral Disc; Perfusion Bioreactor; Scaffolds; Tissue Engineering

$1,170,450

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

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Applying for

Mention their CIHR grant from 2025

Subject: Prospective PhD student: Antisense Oligonucleotide Dear Professor Koch, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. Your research on antisense oligonucleotide connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Determining the safety and efficacy of microRNA-181a-5p blocker as a potential therapy for the treatment of osteoarthritis" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]