Faculty profile
Anita Layton
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Research
Latest papers
Proteomic signatures of loss of glycemic control in youth-onset type 2 diabetes in the TODAY study.
The Journal of clinical endocrinology and metabolism · 2026
Modeling the relation between intraocular pressure and human trabecular meshwork fluid-mechanical properties.
Mathematical biosciences and engineering : MBE · 2026
Interdisciplinary development and application of computational methods in informatics for clinical applications.
Journal of the American Medical Informatics Association : JAMIA · 2026
Latest funding
- $95,000
Enabling evidence-based policymaking and interdisciplinary social change research for homelessness: Developing and evaluating CivicInquire, Canada's first intersectional AI-powered social science platform
SSHRC · 2026 · Co-investigator
- $757,350
Accurate Retinal Oximetry for the Pre-Symptomatic Diagnosis of Major Blinding Diseases
CIHR · 2024 · Co-investigator
- $200,000
Next Generation of Surgical Microscopes for Real-time Virtual Histopathology
NSERC · 2023 · Co-investigator
15 publications.
Proteomic signatures of loss of glycemic control in youth-onset type 2 diabetes in the TODAY study.
Tommerdahl KL, Miller KR, Liu JJ, Choi YJ, Ramesh S, Narongkiatikhun P, Vigers T, D'Antonio M, Weissenkampen D, Hampson HE, Goodrich JA, Pinzon-Cortes JA, Isganaitis E, Lu C, Chen ZZ, El Ghormli L, Nelson RG, Laffel LM, Nguyen N, Liu S, Lim SC, Shah AS, Layton A, Gubitosi-Klug R, Inge TH, Ryder JR, van Raalte D, Nadeau KJ, Bjornstad P, Pyle L
Modeling the relation between intraocular pressure and human trabecular meshwork fluid-mechanical properties.
Sacco R, Chiaravalli G, Guidoboni G, Layton A, Antman G, Verticchio A, Siesky B, Ciulla TA, Harris A
Interdisciplinary development and application of computational methods in informatics for clinical applications.
Albers D, Cato K, Layton A, Rossetti SC
The Transparent Reporting and Evaluation of Artificial Intelligence Models (TRUE-AIM) Report Card: A Quality Assurance Initiative of the American Heart Association Journals to Promote High-Quality, Reproducible Artificial Intelligence Research.
Kolossváry M, Smith EE, Reeves MJ, Layton A, Mills NL, Motwani M, Goto S, Atkins N
scVAEDer: integrating deep diffusion models and variational autoencoders for single-cell transcriptomics analysis.
Sadria M, Layton A
Reduced-Order Model for Cell Volume Homeostasis: Application to Aqueous Humor Production.
Sacco R, Chiaravalli G, Guidoboni G, Layton A, Antman G, Shalem KW, Verticchio A, Siesky B, Harris A
Proteomic Analysis Uncovers Multiprotein Signatures Associated with Early Diabetic Kidney Disease in Youth with Type 2 Diabetes Mellitus.
Pyle L, Choi YJ, Narongkiatikhun P, Sharma K, Waikar S, Layton A, Tommerdahl KL, de Boer I, Vigers T, Nelson RG, Lynch J, Brosius F, Saulnier PJ, Goodrich JA, Tryggestad JB, Isganaitis E, Bacha F, Nadeau KJ, van Raalte D, Kretzler M, Heerspink H, Bjornstad P
Fatecode enables cell fate regulator prediction using classification-supervised autoencoder perturbation.
Sadria M, Layton A, Goyal S, Bader GD
Human Factor Health Data Interoperability.
Affleck E, Sutherland E, Lindeman C, Golonka R, Price T, Murphy T, Williamson T, Chapman A, Layton A, Fraser C
Adversarial training improves model interpretability in single-cell RNA-seq analysis.
Sadria M, Layton A, Bader GD
Enabling evidence-based policymaking and interdisciplinary social change research for homelessness: Developing and evaluating CivicInquire, Canada's first intersectional AI-powered social science platform
Principal investigators: Minaker, Leia
Accurate Retinal Oximetry for the Pre-Symptomatic Diagnosis of Major Blinding Diseases
Principal investigators: Haji Reza, Parsin
Keywords: Biomakers; Biomedical Optics; Optics And Photonics; Oxygen Saturation; Photoacoustic Microscopy; Retinal Oximetry; Retinal Vasculature
Next Generation of Surgical Microscopes for Real-time Virtual Histopathology
Principal investigators: Haji Reza, Parsin
Keywords: optics; biomedical optics; cancer imaging; histology; biology; artificial intelligence; image processing software; machine learning; histogram matching
Next Generation Surgical Microscopes for Rapid Virtual Histopathology
Principal investigators: Haji Reza, Parsin
Keywords: Biomedical Optics; Cancer Imaging; Hematoxylin And Eosin; Histology; Intraoperative Cancer Margin Assessment; Laser; Medical Imaging; Optics And Photonics; Real-Time Biopsy Assessment
Mitochondrial Bioenergetics in the Kidney: Sex-specific Computational Modelling
Principal investigators: Layton, Anita AT
SodiUm Glucose co-trAnspoRt-2 inhibitioN diabeteS And and kidney function Loss in Type 1 diabetes: The "SUGARNSALT" Team Grant Program
Principal investigators: Cherney, David Z; Campbell, David J; Layton, Anita; Perkins, Bruce A
Keywords: Albuminuria; Biological Sex; Blood Pressure; Cardiovascular Disease; Diabetes; Gfr Slope; Glycemic Control; Kidney Health And Disease; Patient Oriented Research; Sglt2 Inhibition
Mapping the Emergence and Functional Impact of Novel SARS-CoV-2 Variants
Principal investigators: Wrana, Jeffrey L
Keywords: Functional Mapping; Sars-Cov-2 Variants; Variant Identification
Learning from incomplete data by combining physiological knowledge and machine learning
Principal investigators: Layton, Anita AT
Keywords: computer simulations; machine learning; physiology; system biology
From data to knowledge: Designing user-driven nutrient loading observatories across the Great Lakes Basin
Principal investigators: Basu, Nandita NB
Keywords: data science; great lakes basin; human impact; machine learning; nitrogen; nutrient pollution; phosphorus; water portal; water quality; watershed modelling
SodiUm Glucose co-trAnspoRt-2 inhibitioN diabeteS And and kidney function Loss in Type 1 diabetes: The "SUGARNSALT" Team Grant Program
Principal investigators: Cherney, David Z; Campbell, David J; Layton, Anita; Perkins, Bruce A
Keywords: Albuminuria; Biological Sex; Blood Pressure; Cardiovascular Disease; Diabetes; Gfr Slope; Glycemic Control; Kidney Health And Disease; Patient Oriented Research; Sglt2 Inhibition
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
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