Anthony Percival-Smith, Western University

Research

Developmental genetics Drosophila development Drosophila genetics Gene expression Gene regulation Regulatory DNA sequences Transcriptional regulation Transcription factors

Latest papers

Rescue of a decapentaplegic hypomorphic wing growth phenotype by expression of the signalling ligands Hedgehog, Semphorin a1 and Wnt homolog 2 in Drosophila melanogaster.
G3 (Bethesda, Md.) · 2026 · first author
The transcriptomics of phenotypic nonspecificity in Drosophila melanogaster.
G3 (Bethesda, Md.) · 2025 · senior author
The frequency and differential pleiotropy of phenotypic nonspecificity in Drosophila melanogaster.
Genetics · 2023 · first author

All 15 publications

Latest funding

Advanced capacity for analysis of nucleic acids in a shared research space
NSERC · 2022 · Co-investigator
$137,057
Phenotypic non-specificity of transcription factor function in Drosophila melanogaster
NSERC · 2021 · Principal investigator
$144,000
Functional dissection of Drosophila homeodomain transcription factors required for development of the body plan.
NSERC · 2015 · Principal investigator
$120,000

All 16 grants and awards

15 publications.

01

Rescue of a decapentaplegic hypomorphic wing growth phenotype by expression of the signalling ligands Hedgehog, Semphorin a1 and Wnt homolog 2 in Drosophila melanogaster.

Percival-Smith A, Brabrook C

G3 (Bethesda, Md.)2026First author

DOI: 10.1093/g3journal/jkag202 PMID: 42504758

02

The transcriptomics of phenotypic nonspecificity in Drosophila melanogaster.

Sidhu G, Percival-Smith A

G3 (Bethesda, Md.)2025Senior author

DOI: 10.1093/g3journal/jkaf215 PMID: 40971887

03

The frequency and differential pleiotropy of phenotypic nonspecificity in Drosophila melanogaster.

Percival-Smith A, Cheng S, Ouellette K

Genetics2023First author

DOI: 10.1093/genetics/iyad056 PMID: 36999545

04

Post-translational modifications of Drosophila melanogaster HOX protein, Sex combs reduced.

Banerjee A, Percival-Smith A

PloS one2020Senior author

DOI: 10.1371/journal.pone.0227642 PMID: 31931520

05

Phenotypic Nonspecificity as the Result of Limited Specificity of Transcription Factor Function.

Percival-Smith A

Genetics research international2018First author

DOI: 10.1155/2018/7089109 PMID: 30510805

06

CRISPR-induced null alleles show that Frost protects Drosophila melanogaster reproduction after cold exposure.

Newman CE, Toxopeus J, Udaka H, Ahn S, Martynowicz DM, Graether SP, Sinclair BJ, Percival-Smith A

The Journal of experimental biology2017Senior author

DOI: 10.1242/jeb.160176 PMID: 28705828

07

The Noncell Autonomous Requirement of Proboscipedia for Growth and Differentiation of the Distal Maxillary Palp during Metamorphosis of Drosophila melanogaster.

Percival-Smith A, Ponce G, Pelling JJ

Genetics research international2017First author

DOI: 10.1155/2017/2624170 PMID: 28357140

08

Non-specificity of transcription factor function in Drosophila melanogaster.

Percival-Smith A

Development genes and evolution2017First author

DOI: 10.1007/s00427-016-0566-z PMID: 27848019

09

A novel screen for genes associated with pheromone-induced sterility.

Camiletti AL, Percival-Smith A, Croft JR, Thompson GJ

Scientific reports2016

DOI: 10.1038/srep36041 PMID: 27786267

10

Differential pleiotropy and HOX functional organization.

Sivanantharajah L, Percival-Smith A

Developmental biology2015Senior author

DOI: 10.1016/j.ydbio.2014.11.001 PMID: 25448696

Advanced capacity for analysis of nucleic acids in a shared research space

Co-investigatorNSERC2022Research Tools and Instruments

Principal investigators: Thorn, R Greg

$137,057

Phenotypic non-specificity of transcription factor function in Drosophila melanogaster

Principal investigatorNSERC2021Discovery Grants Program - Individual

Principal investigators: Percival-Smith, Anthony

Keywords: transcription initiation; gene expression; transcription factors; regulatory dna sequences; transcriptome; gene regulation; developmental genetics; transcriptional regulation; drosophila development; drosophila genetics

$144,000

Functional dissection of Drosophila homeodomain transcription factors required for development of the body plan.

Principal investigatorNSERC2015Discovery Grants Program - Accelerator Supplements

Principal investigators: PercivalSmith, Anthony

$120,000

Functional dissection of Drosophila homeodomain transcription factors required for development of the body plan.

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: PercivalSmith, Anthony

$225,000

MoBEES: a facility for Molecular Studies in Biodiversity, Ecology, and Environmental Sciences

Co-investigatorNSERC2014Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Thompson, Graham

$130,280

Imaging and microscopy suite software and hardware upgrades

Co-investigatorNSERC2011Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Damjanovski, Sashko

$40,469

Request for gradient polymerase chain reaction thermocycler and -86 C Ultra-low freezer

Principal investigatorNSERC2010Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: PercivalSmith, Anthony

$23,033

Functional dissection of drosophila homeodomain transcription factors required for development of the body plan

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: PercivalSmith, Anthony

$165,000

Dissection of drosophila fushi tarazu activity

Principal investigatorNSERC2005Discovery Grants Program - Individual

Principal investigators: PercivalSmith, Anthony

$145,000

Dissection of fushi tarazu activity required for segmentation of Drosophilia

Principal investigatorNSERC2003Discovery Grants Program - Individual

Principal investigators: PercivalSmith, Anthony

$41,600

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

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Applying for

Paper to mentionMention their NSERC grant from 2021

Subject: Prospective PhD student: Developmental genetics Dear Professor Percival-Smith, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Rescue of a decapentaplegic hypomorphic wing growth phenotype by expression of the signalling ligands Hedgehog, Semphorin a1 and Wnt homolog 2 in Drosophila melanogaster." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Phenotypic non-specificity of transcription factor function in Drosophila melanogaster" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]