Faculty profile
Marco Prado
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Research
Read how they describe their research on their Western University profile.
Latest papers
Longitudinal behavioral profiling reveals early-onset and persistent motor dysfunction in a VAChT-KD model for congenital myasthenic syndrome.
Behavioural brain research · 2026
Latest funding
- $998,326
Microstructural brain aging across the lifespan of mice
CIHR · 2025 · Co-investigator
- $1,400,000
Canada Research Chair - Tier 1
CIHR · 2025 · Nominated PI
- $940,950
Role of the co-chaperone STIP1 in alpha-synuclein spreading, aggregation and toxicity
CIHR · 2024 · Nominated PI
1 publications.
Longitudinal behavioral profiling reveals early-onset and persistent motor dysfunction in a VAChT-KD model for congenital myasthenic syndrome.
Barbosa LA, Santos KBS, Marques GH, Miranda AS, Guatimosim S, Prado M, Prado V, Guatimosim C
Microstructural brain aging across the lifespan of mice
Principal investigators: Baron, Corey A; Khan, Ali R
Keywords: Aging; Brain; Diffusion Mri; Lifespan; Light Sheet; Microscopy; Microstructure; Mouse; Mri; Neurodegeneration
Canada Research Chair - Tier 1
Principal investigators: Prado, Marco A
Keywords: Crc
Role of the co-chaperone STIP1 in alpha-synuclein spreading, aggregation and toxicity
Principal investigators: Prado, Marco A
Keywords: Behavior; Chaperones; Cognition; Genetically-Modified Mice; Neurodegeneration; Prion-Like; Synuclein
Alpha synuclein multivalent misfolding-specific peptide vaccine in mouse models of synucleinopathy
Principal investigators: Fernandes da Silva, Caroline
Keywords: Alpha-Synuclein; Immunotheraphy; Parkinson Disease; Propagated Protein Misfolding; Vaccine
Inducing VAChT expression, ApoE2 expression, or their combination, to boost cholinergic function and counteract ApoE4-linked deficits in spatial pattern separation
Principal investigators: Batallán Burrowes, Ariel A
Keywords: Alzheimer'S Disease; Apoe; Cholinergic System; Fiber Photometry; Hippocampus; Light Sheet Microscopy; Mri; Pattern Separation; Touchscreen; Vesicular Acetylcholine Transporter
Understanding how synuclein misfolding induces neuroinflammation
Principal investigators: Mutambayi, Kéligne G
Keywords: Aggregates; Cells; Cellular; Environmental; Inflammatory; Nervous System; Protein; Synuclein
Leveraging deep biology for brain resilience to AD pathology
Principal investigators: Schmitz, Taylor W
Keywords: Alzheimer'S Disease; Brain Resilience; Imaging Biomarkers; Mechanisms Of Action; Mouse Models; P75ntr; Pharmacology; Preclinical Trials
TRIDENT: TRanslational Initiative to DE-risk NeuroTherapeutics
Principal investigators: Menon, Ravi
Keywords: cognition; drug discovery; mouse models; marmoset; organoids; imaging; open science; neurodegenerative disease; neurochemistry; neural circuits; sex differences
Investigating the role of neuronal STI1 co-chaperone in facilitating in vivo a-synuclein toxicity
Principal investigators: Novikov, Vladislav
Keywords: Biochemistry; Cognitive Testing; Dementia; Immunohistochemistry; Mouse Models Of Disease; Neurodegenerative Disease; Neuroscience; Parkinson'S Disease; Protein Misfolding; Treatment
Interactions between hippocampal vesicular acetylcholine transporter (VAChT) loss and amyloid pathology in circuit and cognitive deficits in Alzheimer's disease
Principal investigators: Prado, Marco A
Keywords: Alzheimer'S Disease; Cholinergic Signalling; Cognition; Fibre Photometry; Hippocampus; Miniscope; Neurodegeneration; Pathology; Touchscreens
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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