This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Western University directory, so their courses may be missing. Find their university profile.
Research
Read how they describe their research on their Western University profile.
Latest papers
A phase 1 dose-finding study of intravenous L-citrulline in sickle cell disease: a potential novel therapy for sickle cell pain crisis.
British journal of haematology · 2019
Latest funding
- $745,875
Drug transporters as treatment targets for mushroom poisonings
CIHR · 2022 · Nominated PI
- $1,995,001
Integrated Precision Medicine Technology and Approach for Optimal Drug Therapy for Canadians
CIHR · 2020 · Principal investigator
- $199,221
Sex and genetic determinants of direct-acting oral anticoagulant (DOAC) efficacy and adverse outcomes
CIHR · 2017 · Co-investigator
1 publications.
A phase 1 dose-finding study of intravenous L-citrulline in sickle cell disease: a potential novel therapy for sickle cell pain crisis.
Majumdar S, Tirona R, Mashegu H, Desai J, Shannon NT, Summar M, Cunningham G, Darbari D, Nickel R, Campbell A, Barr FE
Drug transporters as treatment targets for mushroom poisonings
Principal investigators: Tirona, Rommel G
Keywords: Amatoxin; Antidote; Cyclosporin A; Drug Transporters; Hepatotoxicity; Mushroom Poisoning; Phallotoxin; Pharmacokinetics; Rifampin
Integrated Precision Medicine Technology and Approach for Optimal Drug Therapy for Canadians
Principal investigators: Kim, Richard B; Barrett, David R; Bauman, Glenn S; Choi, Yun-Hee; Garg, Amit; Grof-Iannelli, Martie N; Levine, Mark N; Morgan, Bronagh J; Sarma, Sisira K; Schwarz, Ute I; Tirona, Rommel G; Welch, Stephen A; Winquist, Eric
Keywords: Clinical Pharmacology; Drug Interactions; Drug Metabolism; Pharmacogenetics; Pharmacogenomics
Sex and genetic determinants of direct-acting oral anticoagulant (DOAC) efficacy and adverse outcomes
Principal investigators: Schwarz, Ute I
Keywords: Oral Anticoagulation; Sex-Drug-Gene Interaction
Tumour Acidification Treatment: Optimization using pH-Weighted MRI
Principal investigators: Bartha, Robert
Keywords: Acidification; Cancer; Chemical Exchange Saturation Transfer; Glioblastoma Multiforme; Intracellular Ph; Magnetic Resonance Imaging; Metabolism; Phosphorus Magnetic Resonance Spectroscopy; Treatment; Warburg
Clinical and pharmacogenomic predictors of inter-patient variation in direct acting oral anticoagulant (DOAC) plasma concentrations in real-world patients
Principal investigators: Kim, Richard B; Carleton, Bruce C; Tirona, Rommel G
Keywords: Clinical And Pharmacogenomic Predictors
Drug disposition in non-alcoholic fatty liver disease
Principal investigators: Tirona, Rommel G
Keywords: Animal Models; Clinical Pharmacology; Drug Metabolism; Drug Transport; In Vitro Models; Non-Alcoholic Fatty Liver Disease; Transcriptional Regulation
DSEN Pharmacogenomics of Adverse Reaction Events National Team (DSEN-PREVENT)
Principal investigators: Kim, Richard B; Carleton, Bruce C; Ross, Colin J; Tirona, Rommel G
Keywords: Adverse Drug Reactions; Drug Metabolism; Pharmacogenomics; Pharmacokinetics; Pharmacology
Role of Skeletal Muscle Drug Transporters in Statin-Induced Myopathy
Principal investigators: Tirona, Rommel G
Keywords: Drug Transporters; Myopathy; Pharmacokinetics; Statins
The Role of Skeletal Muscle Transporters in Statin-Induced Myopathy
Principal investigators: Knauer, Michael
Keywords: Hmg-Coa Reductase Inhibitor; Myalgia; Myopathy; Pharmacology; Rhabdomyolysis; Statins; Toxicity; Transporters
Hepatic drug uptake mediated by the human organic anion-transporting polypeptides subfamily 1B: molecular and regulatory determinants of clinical drug response
Principal investigators: De Gorter, Marianne K
Keywords: Clinical Pharmacology; Drug Metabolism; Drug Transport; Gene Regulation; Hepatic Drug Uptake; Organic Anion Transporting Polypeptides; Personalized Medicine; Pharmacogenetics; Pharmacokinetics; Translational Medicine
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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